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首页> 外文期刊>Journal of genetics >Analysis of indigenous plasmid sequences ofA. baumanniiDS002 reveals the existence of lateral mobility and extensive genetic recombination amongAcinetobacterplasmids
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Analysis of indigenous plasmid sequences ofA. baumanniiDS002 reveals the existence of lateral mobility and extensive genetic recombination amongAcinetobacterplasmids

机译：土着质粒序列的分析。 Baumanniids002揭示了横向迁移率和广泛的遗传重组的存在易患杆菌

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摘要

Genome sequence ofAcinetobacter baumanniiDS002 revealed the existence of seven contigs with features of indigenous plasmids. Of the seven contigs, three of them have shown size and sequence identity. They appeared to have been generated due to the unique recombination events leading to a large-scale recombination and sequence inversions. The rest of the indigenous plasmids have shown significant size variations and contained the genetic repertoire required for the detoxification of formaldehyde and biosynthesis of exopolysaccharides. Genetic modules encoding novel toxin-antitoxin systems were found in most of the plasmids to ensure their survival in the host. In some instances, the toxin and antitoxin coding sequences were found on two different plasmids promoting the cosegregation of these two plasmids into the daughter cells.
机译：Baumannids002内杆菌的基因组序列显示存在七种具有本土质粒特征的重叠群。在这七只蛤蟆中，有三只显示出大小和序列的一致性。它们似乎是由于独特的重组事件导致大规模重组和序列反转而产生的。其余的本土质粒显示出显著的大小差异，并包含甲醛解毒和胞外多糖生物合成所需的基因库。在大多数质粒中发现了编码新型毒素-抗毒素系统的基因模块，以确保它们在宿主中的存活。在某些情况下，在两种不同的质粒上发现了毒素和抗毒素编码序列，促进了这两种质粒与子细胞的共分离。

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