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首页> 外文期刊>Journal of minimally invasive gynecology >Near-infrared Fluorescence-guided Sentinel Node Mapping of the Ovary With Indocyanine Green in a Minimally Invasive Setting: A Feasible Study
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Near-infrared Fluorescence-guided Sentinel Node Mapping of the Ovary With Indocyanine Green in a Minimally Invasive Setting: A Feasible Study

机译:近红外荧光引导的哨子节点卵巢与吲哚菁绿色的卵巢在微创的环境中:可行的研究

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摘要

Sentinel lymph node (SLN) mapping has increased its feasibility in both early-stage cervical and endometrial cancer. There are few SLN studies regarding the ovary because of the risk of tumor dissemination and perhaps because the ovary represents an inconvenient site for injection. In this preliminary study, we have shown the feasibility of SLN mapping of the ovary with indocyanine green during laparoscopic retroperitoneal aortic surgical staging. The 10 women who were included in this study underwent aortic with pelvic laparoscopic staging, which included SLN biopsy, extrafascial total hysterectomy, and bilateral salpingo-oophorectomy in case of an ovarian tumor. The fluorescent dye was injected on the dorsal and ventral side of the proper ovarian ligament and the suspensory ligament, close to the ovary and just underneath the peritoneum. In all cases except 1, SLNs were detected soon after the injection in the aortic compartment and in 3 cases also in the common iliac region. Only 1 intraoperative complication occurred: a superficial lesion of the vena cava that was recovered with a laparoscopic suture. Laparoscopic ovarian SLN mapping performed by means of an injection of indocyanine green fluorescent tracer in the ovarian ligaments seems feasible and promising. Further investigation are encouraged and necessary to evaluate the possible applications of this new technique for staging patients with early-stage ovarian cancer. (C) 2016 AAGL. All rights reserved.
机译:前哨淋巴结(SLN)定位增加了其在早期宫颈癌和子宫内膜癌中的可行性。关于卵巢的SLN研究很少,因为有肿瘤扩散的风险,可能是因为卵巢是一个不方便注射的部位。在这项初步研究中,我们已经证明了在腹腔镜腹膜后主动脉手术分期期间用吲哚青绿对卵巢进行SLN定位的可行性。纳入本研究的10名女性接受了主动脉和盆腔腹腔镜分期,包括SLN活检、筋膜外全子宫切除术,以及卵巢肿瘤的双侧输卵管卵巢切除术。荧光染料注射在卵巢固有韧带和悬韧带的背侧和腹侧,靠近卵巢,腹膜正下方。在除1例外的所有病例中,注射后不久在主动脉室检测到SLN,3例在髂总区也检测到SLN。术中仅发生1例并发症:腔静脉的浅表病变通过腹腔镜缝合得以恢复。通过在卵巢韧带内注射吲哚青绿荧光示踪剂进行腹腔镜卵巢SLN定位似乎是可行和有希望的。鼓励并有必要进行进一步研究,以评估这项新技术在早期卵巢癌患者分期中的可能应用。(C) 2016年AAGL。版权所有。

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