Anti-N-methyl-D-aspartate receptor encephalitis associated with intracranial cryptococcal infection: A case report and 2-year follow-up

Fang Fang; Wang Ying; Xu Wei

首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Anti-N-methyl-D-aspartate receptor encephalitis associated with intracranial cryptococcal infection: A case report and 2-year follow-up

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Anti-N-methyl-D-aspartate receptor encephalitis associated with intracranial cryptococcal infection: A case report and 2-year follow-up

机译：抗N-甲基-D-天冬氨酸受体脑炎与颅内肾上腺炎相关，案例报告和2年随访

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Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis is a type of autoimmune encephalitis characterized by the rapid onset of neurologic dysfunction. Several studies have reported the important role of post-infectious effect in its pathogenesis. Herein, we report on a 68-year-old woman diagnosed with anti-NMDA receptor encephalitis with concomitant intracranial cryptococcal infection, who was followed up for two years and demonstrated clinical improvements after effective anti-fungal therapy. This case may help expand the clinical spectrum of post-infectious immune-mediated etiology of anti-NMDA receptor encephalitis. The pathogenic role of both disorders requires further investigation.

机译：抗N-甲基-D-天门冬氨酸（Anti-N-methyl-D-aspartate，Anti-NMDA）受体脑炎是一种自身免疫性脑炎，其特征是迅速出现神经功能障碍。一些研究报道了感染后效应在其发病机制中的重要作用。在此，我们报告一名68岁女性，被诊断为抗NMDA受体脑炎并伴有颅内隐球菌感染，经过两年的随访，在有效的抗真菌治疗后，临床症状有所改善。该病例可能有助于扩大抗NMDA受体脑炎感染后免疫介导病因的临床范围。这两种疾病的致病作用需要进一步研究。

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来源
《Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology》 |2021年第1期|共4页
作者
Fang Fang; Wang Ying; Xu Wei;
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作者单位

Shanghai Jiao Tong Univ Ruijin Hosp Dept Geriatr Sch Med Shanghai Peoples R China;

Shanghai Jiao Tong Univ Inst Neurol Ruijin Hosp Dept Neurol Sch Med 197 Ruijin 2nd Rd Shanghai;

Shanghai Jiao Tong Univ Inst Neurol Ruijin Hosp Dept Neurol Sch Med 197 Ruijin 2nd Rd Shanghai;

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原文格式 PDF
正文语种 eng
中图分类神经病学;
关键词
Anti-N-methyl-D-aspartate receptor encephalitis; Intracranial cryptococcal infection; Post-infectious immune-mediated etiology;

机译：抗N-甲基-D-天冬氨酸受体脑炎;颅内隐球菌感染;感染后免疫介导病因学;

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Anti-N-methyl-D-aspartate receptor encephalitis associated with intracranial cryptococcal infection: A case report and 2-year follow-up

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