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SARS-CoV-2 and nervous system: From pathogenesis to clinical manifestation

机译:SARS-COV-2和神经系统:从发病机制到临床表现

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摘要

Since the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a growing body of evidence indicates that besides common COVID-19 symptoms, patients may develop various neurological manifestations affecting both the central and peripheral nervous systems as well as skeletal muscles. These manifestations can occur prior, during and even after the onset of COVID-19 general symptoms. In this Review, we discuss the possible neuroimmunological mechanisms underlying the nervous system and skeletal muscle involvement, and viral triggered neuroimmunological conditions associated with SARS-CoV-2, as well as therapeutic approaches that have been considered for these specific complications worldwide.
机译:2019冠状病毒疾病2019冠状病毒疾病(COVID-19)由于严重急性呼吸综合征冠状病毒2(SARS COV-2)引起,越来越多的证据表明除了常见的COVID-19症状外,患者可能会发展各种影响中枢和外周神经系统以及骨骼肌的神经系统表现。这些症状可发生2019冠状病毒疾病之前、期间和之后。在这篇综述中,我们讨论了神经系统和骨骼肌受累的潜在神经免疫学机制,与SARS-CoV-2相关的病毒引发的神经免疫学疾病,以及全球范围内考虑的治疗这些特定并发症的方法。

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