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首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Epstein-Barr virus infection in a woman with aquaporin-4 seropositive neuromyelitis optica
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Epstein-Barr virus infection in a woman with aquaporin-4 seropositive neuromyelitis optica

机译:在一个女人的epstein-barr病毒感染有水素-4血清阳性神经肌炎Optica

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摘要

Neuromyelitis optica spectrum disorders (NMOSD) are characterised by pathological antibodies to aquaporin-4 water channels of astrocytes, resulting in severe brain and spinal cord injury. Serological evidence suggests that Epstein-Barr virus (EBV) reactivation may contribute to their pathogenesis. We describe an unusual case of a woman with fever, rash and headache preceding an Aquaporin-4 antibody positive longitudinally extensive transverse myelitis. EBV was detected in her cerebrospinal fluid by polymerase chain reaction assay. This case highlights the potential role of EBV in the pathogenesis of NMOSD.
机译:视神经脊髓炎谱系障碍(NMOSD)的特征是星形胶质细胞水通道蛋白-4的病理性抗体,导致严重的脑和脊髓损伤。血清学证据表明,EB病毒(EBV)的重新激活可能有助于其发病机制。我们描述了一例罕见的病例,一名女性在水通道蛋白-4抗体阳性的纵向广泛性横贯性脊髓炎之前出现发热、皮疹和头痛。用聚合酶链反应法在她的脑脊液中检测到EBV。本病例强调了EBV在NMOSD发病机制中的潜在作用。

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