A novel intracochlear injection method for rapid drug delivery to vestibular end organs

Raghu Vishal; Ramakrishna Yugandhar; Burkard Robert F.; Sadeghi Soroush G.

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A novel intracochlear injection method for rapid drug delivery to vestibular end organs

机译：一种新型肠溶液注射方法，用于快速药物递送给前庭末端器官

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摘要

Background: Injection into the inner ear through the round window (RW) or a cochleostomy is a reliable method for delivering drugs or viruses to the cochlea. This method has been less effective for fast deliveries to vestibular end organs.

机译：背景：通过圆窗（RW）或耳蜗造口术将药物或病毒注入内耳是一种可靠的方法。这种方法对于前庭末端器官的快速分娩效果较差。

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来源
《Journal of Neuroscience Methods》 |2020年第1期|共9页
作者
Raghu Vishal; Ramakrishna Yugandhar; Burkard Robert F.; Sadeghi Soroush G.;
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作者单位

SUNY Buffalo Ctr Hearing &

Deafness Dept Commun Disorders &

Sci 137 Cary Hall 3435 Main St;

SUNY Buffalo Ctr Hearing &

Deafness Dept Commun Disorders &

Sci 137 Cary Hall 3435 Main St;

SUNY Buffalo Dept Rehabil Sci Buffalo NY USA;

SUNY Buffalo Ctr Hearing &

Deafness Dept Commun Disorders &

Sci 137 Cary Hall 3435 Main St;

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原文格式 PDF
正文语种 eng
中图分类人体生理学;
关键词
Utricle; Canalostomy; Round window; Oval window; Vestibular evoked potential; Vestibular nerve; VsEP;

机译：胞果;根管造口术;圆窗;椭圆形窗户;前庭诱发电位;前庭神经;VsEP;

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2. Rapid and sensitive liquid chromatography–tandem mass spectrometric method for the quantitative determination of potentially harmful substance 5,5′-oxydimethylenebis (2-furfural) in traditional Chinese medicine injections [J] . Qingce Zang, Yang Gao, Luojiao Huang, 药学学报：英文版 . 2018,第002期
3. Synthesis of hierarchical sieve-like mesoporous silica nanoparticle aggregates via centrifugal method for drug delivery system [J] . Qin Gao, Wensheng Xie, Lingyun Zhao, 中国化学快报（英文版） . 2018,第012期
4. Rapid and simple flow injection analysis tandem mass spectrometric method for the quantification of melphalan in a lipid-based drug delivery system [J] . Mohammed-Saeid Waleed, Michel Deborah, Badea Ildiko, Rapid Communications in Mass Spectrometry: RCM . 2017,第18期

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5. Single-Injection HPLC Method for Rapid Analysis of a Combination Drug Delivery System [J] . Robert M. Tucker, Benjamin W. Parcher, Ella F. Jones, AAPS PharmSciTech . 2012,第2期

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6. State-of-the-art methods in clinical intracochlear drug delivery [J] . Chin Oliver Y., Diaz Rodney C. Current opinion in otolaryngology & head and neck surgery . 2019,第5期

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7. Development of a novel thermosensitve liposome formulation (HaT) with rapid drug release profile and efficient drug delivery against solid tumor [C] . Tatsuaki Tagami, Mark J Ernsting, Shyh-Dar Li, The Second Asian symposium on pharmaceutical sciences and technology . 2011

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A novel intracochlear injection method for rapid drug delivery to vestibular end organs

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