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首页> 外文期刊>Journal of paediatrics and child health >Feasibility and accuracy of cord blood sampling for admission laboratory investigations: A pilot trial
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Feasibility and accuracy of cord blood sampling for admission laboratory investigations: A pilot trial

机译：入学实验室调查的脐带血采样的可行性和准确性：试验试验

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Aim: Phlebotomy losses greatly contribute to anaemia following preterm birth. Therefore, the possibility of drawing initial tests from the placenta seems attractive. There is a lack of literature regarding the feasibility and accuracy of pathology tests taken from umbilical arterial and venous (UAB/UVB) compared to blood collected from the newborn.Methods: UAB and UVB complete blood pictures were compared with the initial neonatal blood test. The relationship between UAB, UVB and neonatal complete blood picture values was determined by Spearman's Rho correlation with absolute values compared by Kruskal-Wallis. P < 0.05 was considered significant.Results: Neonatal haemoglobin, white cell count, immature/total ratio and platelets were significantly correlated to the corresponding values in the UAB and UVB (all P < 0.001). While UAB and UVB haemoglobin and white cell count were similar, both were significantly lower than the neonatal values (P < 0.001 and P = 0.014, respectively). No difference was seen for immature/total ratio and platelet concentrations. UVB blood culture (BC) was feasible (90%), even with delayed cord clamping, and the UVB BC volume was significantly higher (P < 0.001), with a low rate of BC contamination (1.5%).Conclusions: Our findings support the feasibility and accuracy of umbilical blood in place of blood collected from the newborn. This reduces the phlebotomy losses and allows higher blood volume collection which may increase the sensitivity of BC collection.
机译：目的：静脉切开术的丢失在很大程度上导致早产后贫血。因此，从胎盘中提取初始试验的可能性似乎很有吸引力。与从新生儿采集的血液相比，从脐动脉和静脉（UAB/UVB）进行病理检查的可行性和准确性缺乏文献。方法：将UAB和UVB全血图像与新生儿初始血常规进行比较。UAB、UVB和新生儿全血图像值之间的关系由斯皮尔曼的Rho相关性与Kruskal Wallis比较的绝对值确定。P<0.05被认为是显著的。结果：新生儿血红蛋白、白细胞计数、未成熟/总比率和血小板与UAB和UVB中的相应值显著相关（均P<0.001）。虽然UAB和UVB血红蛋白和白细胞计数相似，但均显著低于新生儿值（分别为P<0.001和P=0.014）。未成熟/总比率和血小板浓度没有差异。UVB血培养（BC）是可行的（90%），即使在延迟脐带夹闭的情况下也是如此，UVB BC体积显著更高（P<0.001），BC污染率较低（1.5%）。结论：我们的研究结果支持脐血替代新生儿血液的可行性和准确性。这减少了静脉切开术的损失，并允许更高的血容量采集，这可能会增加BC采集的敏感性。

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