In-depth characterization of monocyte subsets during the course of healthy pregnancy

Pflitsch Caroline; Feldmann Cai Niklaas; Richert Laura; Hagen Sven; Diemert Anke; Goletzke Janina; Hecher Kurt; Jazbutyte Virginija; Renne Thomas; Arck Petra Clara; Altfeld Marcus; Ziegler Susanne

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In-depth characterization of monocyte subsets during the course of healthy pregnancy

机译：在健康怀孕过程中对单核细胞亚群进行深入表征

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摘要

Pregnancy represents an immunological challenge for the maternal immune system. Pregnancy augments innate immune responses, and particularly monocytes contribute to maintaining the balance between proand antiinflammatory immune responses required for the successful sequence of distinct immunological phases throughout pregnancy. Nonetheless, studies that focus on the heterogeneity of monocytes and analyze the alteration of monocyte subsets in a longitudinal approach throughout healthy pregnancies have remained scarce.

机译：怀孕对母体免疫系统来说是一个免疫挑战。怀孕会增强先天免疫反应，尤其是单核细胞有助于维持促炎和抗炎免疫反应之间的平衡，这是在整个怀孕期间不同免疫阶段成功排序所必需的。尽管如此，关注单核细胞异质性和分析健康妊娠期间单核细胞亚群纵向变化的研究仍然很少。

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来源
《Journal of Reproductive Immunology》 |2020年第1期|共10页
作者
Pflitsch Caroline; Feldmann Cai Niklaas; Richert Laura; Hagen Sven; Diemert Anke; Goletzke Janina; Hecher Kurt; Jazbutyte Virginija; Renne Thomas; Arck Petra Clara; Altfeld Marcus; Ziegler Susanne;
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作者单位

Leibniz Inst Expt Virol Heinrich Pette Inst Martinistr 52 D-20251 Hamburg Germany;

Leibniz Inst Expt Virol Heinrich Pette Inst Martinistr 52 D-20251 Hamburg Germany;

Leibniz Inst Expt Virol Heinrich Pette Inst Martinistr 52 D-20251 Hamburg Germany;

Leibniz Inst Expt Virol Heinrich Pette Inst Martinistr 52 D-20251 Hamburg Germany;

Univ Med Ctr Hamburg Eppendorf Dept Obstet &

Fetal Med Martinistr 52 D-20251 Hamburg Germany;

Univ Med Ctr Hamburg Eppendorf Dept Obstet &

Fetal Med Martinistr 52 D-20251 Hamburg Germany;

Univ Med Ctr Hamburg Eppendorf Dept Obstet &

Fetal Med Martinistr 52 D-20251 Hamburg Germany;

Univ Med Ctr Hamburg Eppendorf Inst Clin Chem &

Lab Med Martinistr 52 D-20251 Hamburg Germany;

Univ Med Ctr Hamburg Eppendorf Inst Clin Chem &

Lab Med Martinistr 52 D-20251 Hamburg Germany;

Univ Med Ctr Hamburg Eppendorf Dept Obstet &

Fetal Med Martinistr 52 D-20251 Hamburg Germany;

Leibniz Inst Expt Virol Heinrich Pette Inst Martinistr 52 D-20251 Hamburg Germany;

Leibniz Inst Expt Virol Heinrich Pette Inst Martinistr 52 D-20251 Hamburg Germany;

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原文格式 PDF
正文语种 eng
中图分类妇科学;
关键词
Monocyte subsets; Pregnancy; Immunophenotyping; Pregnancy-related hormones; Intracellular cytokines;

机译：单核细胞亚群;怀孕免疫表型;妊娠相关激素;细胞内细胞因子;

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1. Phenotypic and functional comparison of two distinct subsets of programmable cell of monocytic origin (PCMOs)-derived dendritic cells with conventional monocyte-derived dendritic cells [J] . Babak Beikzadeh, Nowruz Delirezh 中国免疫学杂志（英文版） . 2016,第002期
2. Phenotypic and functional comparison of two dist subsets of programmable cell of monocytic origin （PCMOs）-derived dendritic cells with conventiona monocyte-derived dendritic cells nct [J] . Babak Beikzadeh1, Nowruz Delirezh2 细胞与分子免疫学：英文版 . 2016,第002期
3. Correlation between T lymphocyte subsets in peripheral blood lymphocytes and 2-year all-cause mortality in an apparently healthy elderly Chinese cohort [J] . WANG Yu-hong, ZHANG Jing-yu, QIAO Fang-fang, 中华医学杂志（英文版） . 2012,第006期
4. Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults [J] . Sebastian Seidler, Henning W Zimmermann, Matthias Bartneck, BMC Immunology . 2010,第1期

机译：健康成年人单核细胞亚群和单核细胞相关趋化因子途径的年龄依赖性变化
5. Metabolically Healthy Obesity Is Characterized by a Proinflammatory Phenotype of Circulating Monocyte Subsets [J] . Christou Konstantinos A., Christou Georgios A., Karamoutsios Achilleas, Metabolic syndrome and related disorders . 2019,第5期

机译：代谢性健康肥胖的特征在于循环单核细胞亚群的促炎表型
6. Perspectives of pregnant and postpartum women and obstetric providers to promote healthy lifestyle in pregnancy and after delivery: a qualitative in-depth interview study [J] . Manasa S. Ayyala, Janelle W. Coughlin, Lindsay Martin, BMC Women s Health . 2020,第1期

机译：怀孕和产后妇女和产科提供者的观点促进怀孕健康的生活方式和交付后：一个定性的深入访谈研究
7. In-depth Proteome Characterization of Healthy and Cancerous Chicken Ovarian Tissues [C] . Angelito I. Nepomuceno, James N. Petitte, David C. Muddiman, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：深入的蛋白质组表征健康和癌性鸡卵巢组织
8. Cell subsets and Pathogen Recognition Requirements Involved in the Innate Response of Primary Human Monocytes and Dendritic Cells to Toxoplasma gondii [D] . Tosh, Kevin W. 2015

机译：人类子代单核细胞和树突状细胞对弓形虫的先天反应涉及的细胞亚群和病原体识别要求
9. In-Depth Proteomic Characterization of Classical and Non-Classical Monocyte Subsets [O] . Víctor Segura, M. Luz Valero, Laura Cantero, 2018

机译：经典和非经典单核细胞亚群的深度蛋白质组学表征。
10. Characterization of neutrophil subsets in healthy human pregnancies. [O] . Aloysius Ssemaganda, Lindsay Kindinger, Philip Bergin, 2014

机译：健康人类怀孕中性粒细胞亚群的表征。
11. Isolation of Human Mononuclear Cell Subsets by Counterflow Centrifugal Elutriation (CCE). I. Characterization of B-Lymphocyte-, T-Lymphocyte-, and Monocyte-Enriched Fractions by Flow Cytometric Analysis [R] . Wahl, L. M., Katona, I. M., Wilder, R. L., 1984

机译：逆流离心回流（CCE）分离人单核细胞亚群。 I.通过流式细胞术分析表征B淋巴细胞，T淋巴细胞和单核细胞富集的组分

In-depth characterization of monocyte subsets during the course of healthy pregnancy

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