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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Association of Paroxysmal Supraventricular Tachycardia with Ischemic Stroke: A National Case-Control Study
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Association of Paroxysmal Supraventricular Tachycardia with Ischemic Stroke: A National Case-Control Study

机译：具有缺血性卒中的阵发性静气管的协会：国家病例对照研究

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Background and Purpose: Cardioembolic stroke accounts for approximately 15%20% of all ischemic strokes. Atrial fibrillation constitutes one-half to two-thirds of all cardioembolic stroke events. The association of paroxysmal supraventricular tachycardia (PSVT) with ischemic stroke remains unclear. A national case-control study was conducted to identify the risk factors, including PSVT, for ischemic stroke in Taiwan. Methods: We designed a national case-control study comprising patients diagnosed with ischemic stroke (n = 5633) from 1997 to 2011; each patient from the case group was randomly matched with the control group (n = 30,895) in Taiwan. Data were retrospectively collected from Taiwan's National Health Insurance Research Database, which contains not only claims data on hospitalization, emergency room visits, and outpatient department visits, but also patient characteristics. Results: Logistic regression analysis was used to identify the risk factors for ischemic stroke. Independent risk factors for ischemic stroke included age (in 5-year intervals; odds ratio [OR], 1.76; 95% confidence interval [CI], 173-1.78), the male sex (versus the female sex; OR, 1.88; 95% CI, 1.74-2.01), chronic kidney disease (OR, 3.09; 95% CI, 2.67-3.57), PSVT (OR, 2.05; 95% CI, 1.30-3.19), and aspirin use (OR,.04; 95% CI,.03-0.05). Conclusions: Our study is the first in Taiwan to identify PSVT as a significant risk factor for ischemic stroke. New antithrombotic regimens, including aspirin, can be recommended for the primary prevention of stroke and for reducing the burden of stroke for patients with PSVT.
机译：背景和目的：心源性卒中约占所有缺血性卒中的15%和20%。心房颤动占所有心源性卒中事件的一半至三分之二。阵发性室上性心动过速（PSVT）与缺血性卒中的关系尚不清楚。进行了一项全国病例对照研究，以确定台湾缺血性中风的危险因素，包括PSVT。方法：我们设计了一项全国病例对照研究，包括1997年至2011年诊断为缺血性中风的患者（n=5633）；病例组的每位患者随机与台湾的对照组（n=30895）匹配。这些数据是从台湾国家健康保险研究数据库中回顾性收集的，该数据库不仅包含住院、急诊和门诊的索赔数据，还包含患者特征。结果：Logistic回归分析用于确定缺血性卒中的危险因素。缺血性中风的独立危险因素包括年龄（以5年为间隔；优势比[OR]为1.76；95%可信区间[CI]为173-1.78）、男性（与女性相比；OR为1.88；95%可信区间为1.74-2.01）、慢性肾病（OR为3.09；95%可信区间为2.67-3.57）、PSVT（OR为2.05；95%可信区间为1.30-3.19）和阿司匹林使用（OR为0.04；95%可信区间为0.03-0.05）。结论：我们的研究是台湾首次将PSVT确定为缺血性中风的重要危险因素。新的抗血栓治疗方案，包括阿司匹林，可以被推荐用于中风的一级预防和减轻PSVT患者的中风负担。

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