...
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >COVID-19 and Stroke: Incidence and Etiological Description in a High-Volume Center
【24h】

COVID-19 and Stroke: Incidence and Etiological Description in a High-Volume Center

机译:Covid-19和中风:大容量中心的发病和病因描述

获取原文
获取原文并翻译 | 示例
           

摘要

Background: An increased rate of thrombotic events has been associated to Coronavirus Disease 19 (COVID-19) with a variable rate of acute stroke. Our aim is to uncover the rate of acute stroke in COVID-19 patients and identify those cases in which a possible causative relationship could exist. Methods: We performed a single-center analysis of a prospective mandatory database. We studied all patients with confirmed COVID-19 and stroke diagnoses from March 2nd to April 30th. Demographic, clinical, and imaging data were prospectively collected. Final diagnosis was determined after full diagnostic work-up unless impossible due to death. Results: Of 2050 patients with confirmed SARS-CoV-2 infection, 21 (1.02%) presented an acute ischemic stroke 21 and 4 (0.2%) suffered an intracranial hemorrhage. After the diagnostic work-up, in 60.0% ischemic and all hemorrhagic strokes patients an etiology non-related with COVID-19 was identified. Only in 6 patients the stroke cause was considered possibly related to COVID-19, all of them required mechanical ventilation before stroke onset. Ten patients underwent endovascular treatment; compared with patients who underwent EVT in the same period, COVID-19 was an independent predictor of in-hospital mortality (50% versus 15%; Odds Ratio, 6.67; 95% CI, 1.1-40.4; p 0.04). Conclusions: The presence of acute stroke in patients with COVID-19 was below 2% and most of them previously presented established stroke risk factors. Without other potential cause, stroke was an uncommon complication and exclusive of patients with a severe pulmonary injury. The presence of COVID-19 in patients who underwent EVT was an independent predictor of in-hospital mortality.
机译:背景:血栓性事件的发生率增加与冠状病毒病19(COVID-19)相关,急性卒中的发生率可变。我们的目的是2019冠状病毒疾病患者的急性脑卒中发生率,并确定可能存在因果关系的病例。方法:我们对一个前瞻性强制性数据库进行单中心分析。我们研究了所有2019冠状病毒疾病患者和卒中诊断。前瞻性收集人口统计学、临床和影像学数据。最终诊断在全面诊断检查后确定,除非因死亡而不可能。结果:在2050例确诊SARS-CoV-2感染的患者中,21例(1.02%)出现急性缺血性卒中,21例(0.2%)出现颅内出血。在诊断2019冠状病毒疾病后,60%例缺血性脑卒中和所有出血性中风患者的病因与COVID-19无关。6例脑卒中2019冠状病毒疾病可能与脑卒中前发病有关。10例接受血管内治疗;C2019冠状病毒疾病与住院患者相比,住院死亡率(50%比15%;优势比6.67;95%可信区间,1.1-40.4;P 0.04)。结论:COV2019冠状病毒疾病患者急性卒中的发生率低于2%,且大多数患者均已出现卒中危险因素。在没有其他潜在原因的情况下,中风是一种罕见的并发症,不包括严重肺损伤的患者。COVID-2019冠状病毒疾病患者的死亡率是住院死亡率的独立预测因子。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号