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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Hospital admissions prior to primary intracerebral haemorrhage and relevant factors associated with survival
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Hospital admissions prior to primary intracerebral haemorrhage and relevant factors associated with survival

机译：在原发性脑内出血之前的医院入学以及与生存相关的相关因素

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Background: Identification and modification of risk factors are essential for preventing intracerebral hemorrhage (ICH). Prior hospital admissions provide opportunities to intervene. We reported hospital admissions prior to primary ICH and investigated factors associated with survival. Methods: Cohort design using patient-level data from the Australian Stroke Clinical Registry (2009-2013) linked with hospital administrative datasets from four states (VIC, NSW, WA, QLD). Prior hospital admission is divided into within 90 days and more than 90 days prior to the index ICH event. The International Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification codes were used to define principal diagnoses of previous admissions/presentations and comorbidities. Factors associated with survival after ICH were investigated using Cox proportional hazards regression. Results: Among 15,482 admissions for stroke, 2,098 (14%) had an ICH (median age 76 years, 52% male), 1,732 patients (83%) had a prior hospital admission, including 440 patients (21%) within 90 days of their index ICH admission. Patients with prior admission were older, had more comorbidities, and greater hospital frailty risk score than those without prior admission. Diseases of the circulatory system (14%) were the most common principal diagnoses for hospital admissions prior to ICH. Of the comorbidities associated with survival, neoplasms conferred the greatest hazard of death at 180 days after ICH (adjusted hazard ratio 1.42, 95% confidence interval 1.15 - 1.76, p = 0.001). Conclusion: Hospital presentations in the 90 days prior to ICH are common. Future research should be focussed on identifying opportunities for preventing ICH. (c) 2020 Elsevier Inc. All rights reserved.
机译：背景：识别和修改危险因素对预防脑出血（ICH）至关重要。事先入院为干预提供了机会。我们报告了原发性脑出血之前的住院情况，并调查了与生存相关的因素。方法：队列设计采用澳大利亚卒中临床登记（2009-2013）的患者水平数据，并与四个州（维多利亚州、新南威尔士州、西澳州、昆士兰州）的医院管理数据集相关联。入院前分为指数ICH事件发生前90天内和90天以上。《国际疾病和相关健康问题分类》第十次修订版、澳大利亚修订代码用于定义以往入院/就诊和共病的主要诊断。采用Cox比例风险回归分析与脑出血后生存相关的因素。结果：在15482例脑卒中入院患者中，2098例（14%）有脑出血（中位年龄76岁，52%为男性），1732例（83%）有入院史，其中440例（21%）在入院90天内。与未入院的患者相比，先前入院的患者年龄更大，合并症更多，医院虚弱风险评分更高。循环系统疾病（14%）是ICH入院前最常见的主要诊断。在与生存相关的共病中，肿瘤在ICH后180天死亡的风险最大（调整后的风险比1.42，95%可信区间1.15-1.76，p=0.001）。结论：ICH前90天内的医院表现很常见。未来的研究应侧重于发现预防ICH的机会。（c） 2020爱思唯尔公司版权所有。

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