...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >The Association of Cerebrovascular Disease with Adverse Outcomes in COVID-19 Patients: A Meta-Analysis Based on Adjusted Effect Estimates
【24h】

The Association of Cerebrovascular Disease with Adverse Outcomes in COVID-19 Patients: A Meta-Analysis Based on Adjusted Effect Estimates

机译：Covid-19患者脑血管疾病与不良结果的关联：基于调整后效应估计的META分析

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective: The aim of this study was to address the association between cerebrovascular disease and adverse outcomes in coronavirus disease 2019 (COVID-19) patients by using a quantitative meta-analysis based on adjusted effect estimates. Method: A systematic search was performed in PubMed, Web of Science, and EMBASE up to August 10th, 2020. The adjusted effect estimates were extracted and pooled to evaluate the risk of the unfavorable outcomes in COVID-19 patients with cerebrovascular disease. Subgroup analysis and meta-regression were also carried out. Results: There were 12 studies with 10,304 patients included in our meta-analysis. A significant trend was observed when evaluating the association between cerebrovascular disease and adverse outcomes (pooled effect = 2.05, 95% confidence interval (CI): 1.34-3.16). In addition, the pooled effects showed that patients with a history of cerebrovascular disease had more likelihood to progress fatal outcomes than patients without a history of cerebrovascular disease (pooled effect = 1.78, 95% CI: 1.04-3.07). Conclusion: This study for the first time indicated that cerebrovascular disease was an independent risk factor for predicting the adverse outcomes, particularly fatal outcomes, in COVID-19 patients on the basis of adjusted effect estimates. Well-designed studies with larger sample size are needed for further verification.
机译：目的：本研究的目的是通过基于校正效应估计的定量荟萃分析，探讨2019年冠状病毒病（COVID-19）患者脑血管疾病与不良后果之间的关系。方法：截至2020年8月10日，在PubMed、科学网和EMBASE上进行系统搜索。2019冠状病毒疾病患者的预后不良风险评估和评估。同时进行亚组分析和元回归分析。结果：我们的荟萃分析包括12项研究，共10304名患者。在评估脑血管疾病与不良后果之间的相关性时，观察到一个显著趋势（综合效应=2.05，95%可信区间（CI）：1.34-3.16）。此外，合并效应表明，有脑血管疾病史的患者比没有脑血管疾病史的患者更可能出现致命性结局（合并效应=1.78，95%可信区间：1.04-3.07）。结论：这项研究首次表明脑血管疾病是预测COVID-19患者不良预后的独立危险因素，尤其是致命的结果。需要设计良好、样本量更大的研究进行进一步验证。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号