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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Is smoking a risk factor for bleeding in adult men with cerebral arteriovenous malformations? A single-center regression study from China
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Is smoking a risk factor for bleeding in adult men with cerebral arteriovenous malformations? A single-center regression study from China

机译：在脑动脉畸形的成人男性中吸烟是否会出血？ 来自中国的单中心回归研究

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Objective: To assess whether smoking increases the risk of bleeding in patients with cerebral arteriovenous malformations (CAVM). Material and methods: According to our research plan, 385 CAVM patients admitted to Beijing Tiantan Hospital from December 2015 to January 2018 were included in this study, including 210 bleeding patients and 175 non-bleeding patients. We divided patients into three subgroups of current smok-ers, ex-smokers (those who quit smoking for one year or more) and non-smokers. The relationship between smoking and the risk of CAVM rupture was assessed by univari-ate and multivariate regression analysis. Results: Multivariate regression analysis showed that there was a statistically significant difference between current smoker and non-smoker (OR = 1.87, p = 0.019). Among the covariates of the multivariate regression analysis, the location, combined with blood flow-related intracranial aneurysms and size were related to the risk of CAVM bleeding. Conclusion: Current smoking may increase the risk of CAVM bleeding; however, there was no significant correlation between ex-smoking and CAVM bleeding.
机译：目的：评估吸烟是否会增加脑动静脉畸形（CAVM）患者的出血风险。材料和方法：根据我们的研究计划，2015年12月至2018年1月，北京天坛医院共收治385例CAVM患者，其中出血患者210例，非出血患者175例。我们将患者分为三个亚组，即当前吸烟者、前吸烟者（戒烟一年或一年以上的人）和非吸烟者。通过单变量和多元回归分析评估吸烟与CAVM破裂风险之间的关系。结果：多元回归分析显示，吸烟者和非吸烟者之间存在统计学显著差异（OR=1.87，p=0.019）。在多元回归分析的协变量中，位置、与血流相关的颅内动脉瘤和大小与CAVM出血风险相关。结论：当前吸烟可能增加CAVM出血的风险；然而，戒烟与CAVM出血之间没有显著相关性。

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