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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Carotid Webs in Pediatric Acute Ischemic Stroke
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Carotid Webs in Pediatric Acute Ischemic Stroke

机译：小儿急性缺血性卒中的颈动脉网

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Introduction: Carotid web is a radiographic entity located in the posterior aspect of the origin of the internal carotid arteries, considered to be a pathologic equivalent to intimal fibromuscular dysplasia, and has been implicated in acute ischemic strokes. The mechanism underlying its development is unknown and it remains unclear if this lesion is congenital or acquired. The aim of our study was to determine the frequency of carotid webs in a pediatric population with acute ischemic stroke (AIS). Methods: A retrospective review of neck CTA, MRA, or DSA images in a pediatric population with acute ischemic stroke was performed to determine the occurrence of carotid webs. Two fellowship-trained neurointerventionists performed independent vascular imaging review. Results: We identified forty-seven cases of childhood acute ischemic stroke (55% male; median age, 9 years). Congenital heart disease, sickle cell disease, infection, and recent head/neck trauma were the most common risk factors. Eight of the ischemic stroke cases were located in multiple vascular territories. Neck arterial imaging was undertaken in twenty-four patients. No carotid webs were detected in the studied pediatric stroke population. (The correlation coefficient for the determination of webs was Kappa = 1.00; p < 0.001). Conclusion: This study failed to find evidence that carotid webs are congenital. More studies are needed for a better understanding of carotid web origin, natural evolution, and the potential implications for treatment.
机译：简介：颈动脉网是一种位于颈内动脉起源后方的影像学实体，被认为是与内膜纤维肌肉发育不良相当的病理学表现，并与急性缺血性中风有关。其发生机制尚不清楚，目前尚不清楚这种病变是先天性还是后天性的。我们的研究目的是确定急性缺血性卒中（AIS）患儿颈动脉网的频率。方法：回顾性分析急性缺血性卒中患儿的颈部CTA、MRA或DSA图像，以确定颈动脉网的发生。两名接受过研究金培训的神经干预专家进行了独立的血管成像检查。结果：我们确定了47例儿童急性缺血性卒中（55%为男性，中位年龄9岁）。先天性心脏病、镰状细胞病、感染和近期头颈部创伤是最常见的危险因素。8例缺血性中风患者位于多个血管区域。对24名患者进行了颈部动脉成像。在研究的儿童中风人群中未检测到颈动脉网。（测定腹板的相关系数为Kappa=1.00；p<0.001）。结论：本研究未能找到颈动脉网是先天性的证据。为了更好地了解颈动脉网的起源、自然进化以及对治疗的潜在影响，还需要进行更多的研究。

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