...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Apolipoproteins B and A1 in Ischemic Stroke Subtypes
【24h】

Apolipoproteins B and A1 in Ischemic Stroke Subtypes

机译：载脂蛋白B和A1在缺血性卒中亚型中

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Introduction: Elevated serum apolipoprotein B and the apolipoprotein B/A1 ratio have been associated with ischemic stroke and intracranial atherosclerotic disease. We sought to assess the relationship between serum levels of apolipoprotein B, apolipoprotein A1, and the apolipoprotein B/A1 ratio with ischemic stroke subtypes and large artery atherosclerosis location. Materials and Methods: We evaluated serum apolipoprotein B and apolipoprotein A1 levels in consecutive, statin-naive, adult ischemic stroke patients admitted to an academic medical center in southern India. We evaluated for differences in the mean serum levels of apolipoprotein B, apolipoprotein A1, and the apolipoprotein B/A1 ratio between patients with ischemic stroke attributed to intracranial atherosclerotic disease, extracranial atherosclerotic disease, small vessel disease, and cardioembolism. In secondary analysis, we assessed for differences in these serum apolipoproteins between patients with moderate-severe intracranial atherosclerotic disease and extracranial atherosclerotic disease, irrespective of ischemic stroke subtype. Results: Among the 156 ischemic stroke patients enrolled in this study, there were no significant differences in serum levels of apolipoprotein B, apolipoprotein A1, and the apolipoprotein B /Al ratio between patients with distinct ischemic stroke subtypes. No significant differences were found in serum levels of apolipoprotein B, A1 and the apolipoprotein B/A1 ratio between patients with moderate-severe intracranial atherosclerotic disease and moderate-severe extracranial atherosclerotic disease. Discussion: Serum levels of apolipoprotein B and A1 did not differ between ischemic stroke subtypes. Additional studies are needed to validate our findings and to better understand the relationship between serum apolipoproteins and stroke.
机译：导言：血清载脂蛋白B和载脂蛋白B/A1比值升高与缺血性中风和颅内动脉粥样硬化疾病有关。我们试图评估血清载脂蛋白B、载脂蛋白A1水平和载脂蛋白B/A1比值与缺血性中风亚型和大动脉动脉粥样硬化部位之间的关系。材料和方法：我们评估了印度南部一个学术医学中心收治的连续、未服用他汀类药物的成年缺血性中风患者的血清载脂蛋白B和载脂蛋白A1水平。我们评估了因颅内动脉粥样硬化性疾病、颅外动脉粥样硬化性疾病、小血管疾病和心脏栓塞导致的缺血性中风患者之间载脂蛋白B、载脂蛋白A1的平均血清水平和载脂蛋白B/A1比值的差异。在二级分析中，我们评估了中重度颅内动脉粥样硬化性疾病和颅外动脉粥样硬化性疾病患者的血清载脂蛋白的差异，而不考虑缺血性卒中亚型。结果：在本研究登记的156名缺血性卒中患者中，不同缺血性卒中亚型患者的血清载脂蛋白B、载脂蛋白A1水平和载脂蛋白B/Al比值没有显著差异。中重度颅内动脉粥样硬化性疾病和中重度颅外动脉粥样硬化性疾病患者血清载脂蛋白B、A1水平及载脂蛋白B/A1比值无显著差异。讨论：血清载脂蛋白B和A1水平在缺血性中风亚型之间没有差异。需要更多的研究来验证我们的发现，并更好地理解血清载脂蛋白与中风之间的关系。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号