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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Otogenic Lateral Sinovenous Thrombosis in Children: A Case Series from a Single Centre and Narrative Review
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Otogenic Lateral Sinovenous Thrombosis in Children: A Case Series from a Single Centre and Narrative Review

机译：儿童卵细胞横向巨大血栓形成：单一中心和叙事评论的案例系列

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摘要

Aim: We aimed to describe otogenic lateral sinovenous thrombosis (OLST), a rare, potentially life-threatening complication of otomastoiditis. Methods: Children diagnosed with OLST in a tertiary-care Hospital from 2014 to 2019 was retrospectively selected. Clinical and radiological features, timing of diagnosis, treatment and outcome are reported. Results: Seven children (5 males) were studied. Fever and neurological symptoms (headache, lethargy, diplopia, dizziness and papilledema) were always present. Otalgia and/or otorrhea were found in 6 children; none had signs of mastoiditis. Diagnosis was reached after 7 days (median) from clinical onset. Brain CT-scan was performed in 5 children being diagnostic for 3. Venography-MRI detected OLST and mastoiditis in all cases without parenchymal lesions. Treatment was based on intravenous rehydration, antibiotic and low-molecular weight heparin; acetazolamide was added in 3 children. Mastoidectomy and ventriculoperitoneal-shunting were selectively performed. Patients were discharged after 26 days (median). Follow-up neuroimaging showed sinus recanalization after a median time of 6 months. Conclusion: A multidisciplinary approach is needed to optimize diagnostic-therapeutic protocols of pediatric OLST.
机译：目的：我们的目的是描述耳源性侧窦静脉血栓形成（OLST），一种罕见的、可能危及生命的耳乳突炎并发症。方法：回顾性选择2014年至2019年在一家三级医院确诊为OLST的儿童。报告临床和放射学特征、诊断时间、治疗和结果。结果：研究对象为7名儿童（5名男性）。发烧和神经症状（头痛、嗜睡、复视、头晕和乳头水肿）总是存在。6名儿童出现耳痛和/或耳漏；没有人有乳突炎的迹象。临床发病7天后（中位数）确诊。5例儿童进行了脑部CT扫描，诊断为3例。静脉造影MRI在所有无实质性病变的病例中检测到OLST和乳突炎。治疗基于静脉补液、抗生素和低分子肝素；3名儿童服用乙酰唑胺。选择性进行乳突切除术和脑室腹腔分流术。患者在26天后出院（中位数）。随访的神经影像学显示，平均6个月后，鼻窦再通。结论：需要一种多学科的方法来优化儿童OLST的诊断治疗方案。

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