• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Risk Factors and Outcomes of Stroke-Associated Pneumonia in Patients with Stroke and Acute Large Artery Occlusion Treated with Endovascular Thrombectomy
【24h】

Risk Factors and Outcomes of Stroke-Associated Pneumonia in Patients with Stroke and Acute Large Artery Occlusion Treated with Endovascular Thrombectomy

机译：血管内血管切除术治疗中风和急性大动脉闭塞患者中风关联肺炎的危险因素及结果

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background and Purpose: Stroke-associated pneumonia (SAP) often increases high hospital mortality, prolongs length of hospital stay, and has considerable economic impact on healthcare costs. We aimed to explore independent predictors of SAP in acute anterior large artery occlusion patients who treated with endovascular treatment (EVT). Methods: Consecutive patients with acute anterior large artery occlusion stroke who underwent EVT from the Nanjing Stroke Registry from January 2019 to January 2020 were identified retrospectively. Patients were divided into SAP group and Non-SAP group. In the univariate analysis, variables including demographics, clinical factors, labs, and EVT features were compared between the two groups. Then a multivariable logistic regression analysis was conducted to determine independent predictors of SAP. Results: One hundred and twelve patients were enrolled. Patients with SAP, compared to those without SAP, had lower modified treatment in cerebral infarction (mTICI) score 2b-3 rate (54.8% vs 85.2%; P = 0.001), higher asymptomatic intracerebral hemorrhage rate (48.4% vs 28.4%; P = 0.046), lower modified Rankin Scale (mRS) score 0-2 rate at 90days rate (9.7% vs 60.5%; P < 0.001), and higher mortality at 90days (38.7% vs 11.1%; P = 0.001). The independent predictors of SAP were dysphagia (Unadjusted Odds ratio[OR] 6.49, 95% Confidence interval[CI] 2.49-16.92; P = 0.02; Adjusted OR 3.59, 95% CI 1.19-10.83; P = 0.02), neutrophil-lymphocyte ratio (Unadjusted OR 1.19, 95% CI 1.1-1.3; P = 0.001; Adjusted OR 1.15, 95% CI 1.06-1.25; P = 0.001), and mTICI 2b-3 (Unadjusted OR 0.21, 95% CI 0.08-0.54; P = 0.001; Adjusted OR 0.3, 95% CI 0.1-0.92; P = 0.04). Conclusion: Dysphagia, higher neutrophil-lymphocyte ratio, and failed recanalization were associated with SAP in acute ischemic stroke patients underwent endovascular therapy. Identification and prevention of SAP was necessary and important.
机译：背景和目的：中风相关肺炎（SAP）通常会增加高医院死亡率，延长住院时间，并对医疗成本产生相当大的经济影响。我们的目的是在接受血管内治疗（EVT）的急性前大动脉闭塞患者中探索SAP的独立预测因子。方法：回顾性分析2019年1月至2020年1月在南京卒中登记处接受EVT治疗的急性前大动脉闭塞性卒中患者。患者分为SAP组和非SAP组。在单变量分析中，比较了两组之间的人口统计学、临床因素、实验室和EVT特征等变量。然后进行多变量逻辑回归分析，以确定SAP的独立预测因素。结果：纳入112例患者。与无SAP的患者相比，SAP患者的脑梗死改良治疗（mTICI）评分2b-3率较低（54.8%对85.2%；P=0.001），无症状脑出血率较高（48.4%对28.4%；P=0.046），90天时改良Rankin评分（mRS）评分0-2率较低（9.7%对60.5%；P<0.001），90天时死亡率较高（38.7%对11.1%；P=0.001）。SAP的独立预测因子为吞咽困难（未经调整的优势比[OR]6.49，95%可信区间[CI]2.49-16.92；P=0.02；经调整的OR 3.59，95%可信区间1.19-10.83；P=0.02）、中性粒细胞淋巴细胞比率（未经调整的OR 1.19，95%可信区间1.1-1.3；P=0.001；经调整的OR 1.15，95%可信区间1.06-1.25；P=0.001），和mTICI 2b-3（未调整或0.21，95%可信区间0.08-0.54；P=0.001；调整或0.3，95%可信区间0.1-0.92；P=0.04）。结论：在接受血管内治疗的急性缺血性卒中患者中，吞咽困难、中性粒细胞-淋巴细胞比率升高和再通失败与SAP有关。SAP的识别和预防是必要和重要的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号