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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Risk Factors in Ischemic Stroke Subtypes: A Community-Based Study in Brno, Czech Republic
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Risk Factors in Ischemic Stroke Subtypes: A Community-Based Study in Brno, Czech Republic

机译：缺血性卒中亚型的危险因素：捷克布尔诺布尔诺的社区研究

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Background: It is not known if risk factors differ between ischemic stroke (IS) subtypes in Central and Eastern Europe. Aims: We performed a community-based analysis of risk factors in patients admitted with IS over a 1 year period in Brno, the second largest city in the Czech Republic (CR). Methods: Based on the National Register of Hospitalized Patients, all patients with IS admitted in Brno in 2011 were identified. Comprehensive discharge summaries from hospital admissions were collected and reviewed. IS subtype and relevant risk factors were ascertained for all patients. The age- and sex-adjusted association of risk factors with IS subtypes was determined. Results: Overall, 682 patients with IS were admitted in 2011 to Brno hospitals. The distribution of IS subtypes was: 35% cardioembolism, 28% large-artery atherosclerosis, 23% small-artery occlusion, 7% stroke of undetermined etiology, 7% stroke of other determined etiology. Several of the risk factors showed high prevalence in the overall sample - e.g. hypertension (84%) and hyperlipidemia (61%). Cardioembolism as compared to other subtypes was positively associated with a history of myocardial infarction, cardiac failure, and atrial fibrillation. Small-artery occlusion was positively associated with history of dementia. No significant association was found between IS subtypes and history of IS, hypertension, diabetes, obesity, alcohol abuse or smoking. Conclusions: We found high frequency of stroke risk factors in all IS subtypes. These findings have implications for stroke prevention strategies in the CR and across Central Europe.
机译：背景：目前尚不清楚中欧和东欧缺血性中风（is）亚型的危险因素是否不同。目的：我们在捷克共和国第二大城市布尔诺（CR）进行了一项为期1年的基于社区的IS患者风险因素分析。方法：根据国家住院患者登记簿，确定2011年Brno收治的所有IS患者。收集并审查住院患者的综合出院总结。确定所有患者的IS亚型和相关危险因素。确定了经年龄和性别调整的危险因素与IS亚型的关联。结果：2011年，共有682名IS患者入住Brno医院。IS亚型的分布为：35%的心源性栓塞，28%的大动脉硬化，23%的小动脉闭塞，7%的病因不明的中风，7%的其他病因确定的中风。一些风险因素在整个样本中的患病率较高，例如高血压（84%）和高脂血症（61%）。与其他亚型相比，心肌栓塞与心肌梗死、心力衰竭和心房颤动病史呈正相关。小动脉闭塞与痴呆病史呈正相关。未发现IS亚型与IS、高血压、糖尿病、肥胖、酗酒或吸烟史之间存在显著相关性。结论：我们在所有IS亚型中发现了高频率的卒中危险因素。这些发现对CR和整个中欧的中风预防策略具有启示。

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