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首页> 外文期刊>Journal of the advanced practitioner in oncology >A Pharmacist-Led Oral Chemotherapy Program’s Impact on Chronic Myeloid Leukemia Patient Satisfaction, Adherence, and Outcomes
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A Pharmacist-Led Oral Chemotherapy Program’s Impact on Chronic Myeloid Leukemia Patient Satisfaction, Adherence, and Outcomes

机译：药剂师LED口腔化疗计划对慢性骨髓白血病患者满意度，依从性和结果的影响

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Patients with chronic myeloid leukemia (CML) can be treated with oral tyrosine kinase inhibitors (TKIs). Pharmacist-led oral chemotherapy programs (POCPs) can improve TKI adherence rates, but evaluation of patient satisfaction with such programs is rare. The purpose of this analysis was to compare the satisfaction of patients with CML taking TKIs enrolled in a POCP program with that of those not enrolled. Secondary objectives were to assess adherence rates, patient-reported value, early molecular response (EMR) rates, and major molecular response (MMR) rates. This study utilized an anonymous telephone survey of patients who had taken TKIs for at least 3 months. Molecular response was determined by chart review. Of 40 patients surveyed, 50% were enrolled in the POCP, and the POCP group had more African Americans than the non-POCP group. More patients in the POCP were satisfied with their care than in the non-POCP group (100% vs. 75%, p = .047). There were no differences in high patient-reported adherence (55% vs. 60%, p = 1.000), patient-reported value for integrated services (95% vs. 90%, p = 1.000), achievement of EMR (75% vs. 75%, p = 1.000), or MMR (85% vs. 85%, p = 1.000). Patients in the POCP received more structured clinical pharmacy services; however, both groups felt the clinical pharmacist played a major role in their care (85% vs. 90%, p = 1.000). Patients in the non-POCP group reported lower satisfaction than those enrolled resulting from fragmented care that was likely due to external specialty pharmacies. Irrespective of POCP enrollment, patients reported clinical pharmacists play a major role in their therapy and value integration of their specialty pharmacy and medical team.
机译：慢性粒细胞白血病（CML）患者可使用口服酪氨酸激酶抑制剂（TKIs）治疗。药剂师主导的口服化疗方案（POCP）可以提高TKI的依从率，但很少评估患者对此类方案的满意度。本分析的目的是比较参加POCP计划和未参加POCP计划的CML患者服用TKI的满意度。次要目标是评估依从率、患者报告值、早期分子反应（EMR）率和主要分子反应（MMR）率。本研究采用匿名电话调查的方法，对服用TKIs至少3个月的患者进行调查。分子反应通过图表分析确定。在接受调查的40名患者中，50%的患者参加了POCP，POCP组的非裔美国人多于非POCP组。POCP组患者对护理的满意度高于非POCP组（100%对75%，p=0.047）。在患者报告的高依从性（55%对60%，p=1.000）、患者报告的综合服务价值（95%对90%，p=1.000）、EMR实现率（75%对75%，p=1.000）或MMR（85%对85%，p=1.000）方面没有差异。POCP患者接受了更结构化的临床药学服务；然而，两组人都认为临床药剂师在他们的护理中发挥了重要作用（85%对90%，p=1.000）。非POCP组患者的满意度低于登记组患者，这可能是由于外部专业药店导致的零散护理。无论POCP注册情况如何，患者报告临床药剂师在他们的治疗和专业药房和医疗团队的价值整合中发挥着重要作用。

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