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The Status of Chemotherapy in Metastatic Breast Cancer: Insights for the Advanced Practitioner

机译:转移性乳腺癌化疗的现状:先进科学公司的见解

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Breast cancer is the most frequently diagnosed cancer in the United States and ranks second as the most common cause of cancer-related death among women (Siegel et al., 2020). According to American Cancer Society (ACS) estimates, approximately 276,480 new cases of breast cancer would have been diagnosed in 2020, and greater than 42,000 deaths would be attributed to breast cancer (ACS, 2020). Although only 7% of all cancer-related deaths are from breast cancer every year, it is the leading cause of death among women between the ages of 40 and 49 years (Siegel et al., 2020). The death rate associated with breast cancer, however, has decreased by 1.3% annually from 2013 to 2017. While improvements in treatment and management coupled with early detection have accounted for the decreased death rate, as of January 2020, there were more than 3.5 million women with a history of breast cancer in the United States (ACS, 2020). Indeed, a vast majority of women with newly diagnosed breast cancer have localized or regional disease that is associated with almost 99% to 85.7% 5-year survival rates, respectively (ACS, 2020).
机译:乳腺癌是美国最常见的癌症,在女性癌症相关死亡中排名第二(Siegel等人,2020年)。根据美国癌症协会(ACS)的估计,2020年将有大约276480例新的乳腺癌病例被诊断出来,超过42000例死亡将归因于乳腺癌(ACS,2020)。尽管每年与癌症相关的死亡人数中只有7%来自乳腺癌,但它是40至49岁女性的主要死因(Siegel等人,2020年)。然而,从2013年到2017年,与乳腺癌相关的死亡率每年下降1.3%。虽然治疗和管理的改善加上早期发现是死亡率下降的原因,但截至2020年1月,美国有350多万女性有乳腺癌病史(ACS,2020年)。事实上,绝大多数新诊断乳腺癌的女性都患有局部或区域性疾病,其5年生存率分别为99%至85.7%(ACS,2020)。

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