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Managing Relapsed Disease in Peripheral T-Cell Lymphoma: Highlights From SOHO 2020

机译:在外周T细胞淋巴瘤中进行复发疾病:来自SOHO 2020的亮点

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摘要

Outcomes for relapsed peripheral T-cell lymphoma (PTCL) have been largely defined by the utility of stem cell transplant, wherein retrospective analyses illustrate relatively limited benefit from autologous transplant (Horwitz et al., 2005; Zele-netz et al., 2003). Allogeneic transplant, on the other hand, offers both progression-free survival and overall survival advantages. There is, however, a significant risk of transplant-related mortality that makes this treatment option reasonable for only a highly select subset of relapsed PTCL patients (Goldberg et al., 2012; Mehta-Shah et al., 2017).
机译:复发性外周T细胞淋巴瘤(PTCL)的预后在很大程度上取决于干细胞移植的效用,其中回顾性分析表明自体移植的益处相对有限(Horwitz等人,2005年;Zele netz等人,2003年)。另一方面,异基因移植具有无进展生存和总体生存优势。然而,存在与移植相关的死亡率的显著风险,这使得该治疗方案仅适用于高度选择性的复发性PTCL患者子集(Goldberg et al.,2012;Mehta Shah et al.,2017)。

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