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A method for estimating the transmissibility of influenza using serial cross-sectional seroepidemiological data

机译:使用串行横截面血型化数据估算流感传导性的方法

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Background: Seroepidemiological surveillance data has been demonstrated to be useful for estimating the cumulative incidence of influenza, and measures the difference between pre- and post-epidemic seropositive fractions. Despite this, such studies relied on a chosen cut-off value for seropositivity. The aim of the present study is to develop a method to analyze distributions of serial cross-sectional seroepidemiological surveillance datasets using an epidemiological model so that the transmission potential can be estimated without imposing a cut-off value.
机译:背景:血清流行病学监测数据已被证明有助于估计流感的累积发病率,并测量流行前和流行后血清阳性率之间的差异。尽管如此,这些研究还是依赖于选定的血清阳性临界值。本研究的目的是开发一种方法,使用流行病学模型分析连续横断面血清流行病学监测数据集的分布,以便在不施加截止值的情况下估计传播潜力。

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