Development of lacrimal gland spheroids for lacrimal gland tissue regeneration

Massie Isobel; Spaniol Kristina; Barbian Andreas; Geerling Gerd; Metzger Marco; Schrader Stefan

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Development of lacrimal gland spheroids for lacrimal gland tissue regeneration

机译：泪腺腺体球泪腺组织再生的发展

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Severe dry eye syndrome resulting from lacrimal gland (LG) dysfunction can cause blindness, yet treatments remain palliative. In vitro reconstruction of LG tissue could provide a curative treatment. We aimed to combine epithelial cells with endothelial cells and mesenchymal stem cells (MSCs) to form a 3D functional unit.

机译：由泪腺（LG）功能障碍引起的严重干眼综合征可导致失明，但治疗仍然是姑息性的。LG组织的体外重建可以提供一种治疗方法。我们的目的是将上皮细胞、内皮细胞和间充质干细胞（MSCs）结合起来，形成一个3D功能单元。

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《Journal of tissue engineering and regenerative medicine》 |2018年第4期|共9页
作者
Massie Isobel; Spaniol Kristina; Barbian Andreas; Geerling Gerd; Metzger Marco; Schrader Stefan;
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作者单位

Univ Clin Dusseldorf Lab Expt Ophthalmol Dusseldorf Germany;

Univ Clin Dusseldorf Eye Clin Dusseldorf Germany;

Univ Clin Dusseldorf Div Clin Anat Dusseldorf Germany;

Univ Clin Dusseldorf Eye Clin Dusseldorf Germany;

Univ Hosp Wurzburg Branch Fraunhofer Inst Interfacial Engn &

Biotech Translat Ctr Regenerat;

Univ Clin Dusseldorf Lab Expt Ophthalmol Dusseldorf Germany;

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正文语种 eng
中图分类基础医学;
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2. Immunoglobulin G4 Positive Mucosa-associated Lymphoid Tissue Lymphoma of the Lacrimal Gland [J] . Jing Li, Xin Ge, Jian-Min Ma, 中华医学杂志（英文版） . 2015,第014期
3. Association of TCR-signaling pathway with the development of lacrimal gland benign lymphoepithelial lesions [J] . Jian-Min, Ma, Yi-Xin, 国际眼科杂志：英文版 . 2015,第004期
4. Similar therapeutic effects of^(125I)seed radiotherapy andγ-ray radiotherapy on lacrimal gland adenoid cystic carcinoma [J] . Rui Liu, Ji-Tong Shi, Xin Ge, 国际眼科杂志：英文版 . 2021,第004期
5. Clinical analysis of 109 cases of lacrimal gland pleomorphic adenoma [J] . Rui Liu, Nan Wang, Hong Zhang, 国际眼科杂志：英文版 . 2021,第012期
6. Development of lacrimal gland spheroids for lacrimal gland tissue regeneration [J] . Massie Isobel, Spaniol Kristina, Barbian Andreas, Journal of tissue engineering and regenerative medicine . 2018,第4期

机译：泪腺腺体球泪腺组织再生的发展
7. Development of Causative Treatment Strategies for Lacrimal Gland Insufficiency by Tissue Engineering and Cell Therapy. Part 1: Regeneration of Lacrimal Gland Tissue: Can We Stimulate Lacrimal Gland Renewal In Vivo? [J] . Dietrich Jana, Massie Isobel, Roth Mathias, Current Eye Research . 2016,第9期

机译：通过组织工程和细胞治疗发展泪腺功能不全的病因治疗策略。第1部分：泪腺组织的再生：我们可以刺激体内的泪腺更新吗？
8. Formation of functionally competent 3D lacrimal gland cell spheroids - towards regeneration of lacrimal gland tissue [J] . Massie Isobel, Spaniol Kristina, Geerling Gerd, Investigative ophthalmology & visual science . 2016,第12期

机译：功能性竞争力的3D泪腺细胞球体 - 朝向泪腺组织的再生
9. In vivo radionuclide assessment of morpho-functional lacrimal gland [C] . Yu. V. Falina, V. A. Obodov, V. V. Pankin, International Young Researchers Conference . 2018

机译：体内放射性核素的语气功能性泪腺的评估
10. An in vitro evaluation of various biomaterials for the development of a tissue-engineered lacrimal gland. [D] . Selvam, Shivaram. 2008

机译：各种生物材料对组织工程泪腺发育的体外评估。
11. Lacrimal gland development: from signaling interactions to regenerative medicine [O] . Ankur Garg, Xin Zhang -1

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12. Lacrimal gland development: From signaling interactions to regenerative medicine [O] . Ankur Garg, Xin Zhang 2017

机译：泪腺发育：从信号相互作用到再生医学
13. Development, Ultrastructure, and Activity of the Foveal Glands and Foveae Dorsales of the Camel Tick, Hyalomma dromedarii (Acari: Ixodidae). 1. Primordial Growth and Gland Formation. [R] . Khalil, G. M., Sonenshine, D. E., Homsher, P. J., 1983

机译：骆驼蜱的发育，超微结构和活动，骆驼蜱，Hyalomma dromedarii（蜱螨亚纲：Ixodidae）。 1.原始生长和腺体形成。

Development of lacrimal gland spheroids for lacrimal gland tissue regeneration

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