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Biomaterials for breast reconstruction: Promises, advances, and challenges

机译:乳房重建生物材料:承诺,进步和挑战

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摘要

Breast reconstruction is the opportunity that provides the chance of having breast after undergoing surgical removal of the breast tissue due to cancer-related surgery. However, this varies on the stage of the cancer diagnosis and the procedure undertaken. There are many regenerative medicine methods that provide several initiatives and direct solutions to problems such as the development of "bioactive tissue," which can regenerate adipose tissues with similar normal functions and structures. There have been several studies which have previously explored for the improvement of breast reconstruction including different variations of biomaterials, different fabrication and processing techniques, cells as well as growth factors which enable bioengineers and tissue engineers to reconstruct a suitable breast for patients with breast cancer. Many factors such as shape, proper volume, mechanical properties have been studies but very scattered with not adequate solution for existing patients worldwide. This review article aims to cover recent advances in the biomaterials, which can be used for reconstruction of breasts as well as looking at the various factors that might lead to individuals needing reconstruction and the materials that are available. The focus would be to look at the various biomaterials that are available to use for reconstruction, their properties, and their structural integrity.
机译:乳房重建是指在因癌症相关手术切除乳房组织后,有机会获得乳房的机会。然而,这取决于癌症诊断的阶段和进行的程序。有许多再生医学方法为诸如“生物活性组织”的开发等问题提供了多项倡议和直接解决方案,这些组织可以再生具有类似正常功能和结构的脂肪组织。此前已经有几项研究探索了乳房重建的改进,包括生物材料的不同变体、不同的制造和加工技术、细胞以及生长因子,使生物工程师和组织工程师能够为乳腺癌患者重建合适的乳房。许多因素,如形状、合适的体积、机械性能等,都已被研究过,但非常分散,没有足够的解决方案用于世界范围内现有的患者。这篇综述文章的目的是介绍可用于乳房重建的生物材料的最新进展,以及可能导致个体需要重建的各种因素和可用的材料。重点是研究可用于重建的各种生物材料、它们的性质和结构完整性。

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