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首页> 外文期刊>Journal of Medical Imaging and Health Informatics >Effect Evaluation of Combined Application of Magnetic Resonance Diffusion Tensor Imaging and Brain Function Imaging in Radiation Therapy of Brain Tumours Involving Motor Pathways
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Effect Evaluation of Combined Application of Magnetic Resonance Diffusion Tensor Imaging and Brain Function Imaging in Radiation Therapy of Brain Tumours Involving Motor Pathways

机译：磁共振扩散张量成像和脑功能成像在涉及电机途径脑肿瘤辐射治疗中的磁共振扩散张量成像和脑功能成像的效果评价

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This study is an attempt to find a way for functional imaging information to be applied clinically in radiation therapy. The basal nucleus is a collective term for a group of neural nucleus in the central nervous system that connects the pontine, brainstem, and cerebral cortex, including the caudate nucleus, the bean-shaped nucleus, the screen-shaped nucleus, and the amygdala. It is difficult to find the exact position of these neural nuclei on the computed tomography (CT) image or the T1 or T2 sequence of magnetic resonance. However, the development of neurosurgery has partially confirmed that these functional nuclei are involved in advanced cognitive functions such as memory, emotion, and learning. Neurosurgery has tried to avoid damaging these nucleus groups during surgery to improve the quality of life of patients, and there is currently no clear strategy for this in radiotherapy. Because CT and magnetic resonance spin echo (SE) sequences are difficult to find the anatomical location of the nucleus, it is difficult to have any strategy to protect these functions in radiotherapy planning. This article uses diffusion tensor imaging (DTI) images and fiber bundle tracking to obtain a more accurate anatomical position of the nerve nucleus on the image, and provides some available strategies for radiotherapy to protect patients' brain function. The conclusion of this paper is that the combined application of DTI and functional magnetic resonance imaging (fMRI) can better observe the relationship among tumours, functional areas and white matter fibers, and guide the designation of radiotherapy plans.
机译：本研究旨在寻找一种将功能成像信息应用于放射治疗临床的方法。基底核是中枢神经系统中连接脑桥、脑干和大脑皮质的一组神经核的统称，包括尾状核、豆状核、屏状核和杏仁核。在计算机断层扫描（CT）图像或磁共振T1或T2序列上很难找到这些神经核的确切位置。然而，神经外科的发展已经部分证实，这些功能核参与高级认知功能，如记忆、情绪和学习。神经外科一直试图避免在手术中损伤这些核团，以提高患者的生活质量，目前在放射治疗中没有明确的策略。由于CT和磁共振自旋回波（SE）序列很难找到细胞核的解剖位置，因此在放射治疗计划中很难有任何策略来保护这些功能。本文利用扩散张量成像（DTI）图像和纤维束追踪技术，获得了更准确的神经核在图像上的解剖位置，并为放射治疗提供了一些可行的策略，以保护患者的脑功能。本文的结论是，DTI和功能磁共振成像（fMRI）的联合应用可以更好地观察肿瘤、功能区和白质纤维之间的关系，并指导放射治疗计划的制定。

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