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Synthesis of cello-oligosaccharides by depolymerization of cellulose: A review

机译:纤维素解聚的基础寡糖合成:综述

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摘要

Cello-oligosaccharides (COS) are small carbohydrate molecules derived from cellulose through partial hydrolysis. COS exert physiological influence on plants, animals and humans when externally dosed or consumed. Their potential as a prebiotic for humans and animals and as an elicitor for plants has generated interest in their synthesis and purification. Currently, their lack of availability, even at scales necessary for research, has restricted the progress in this field. In this review, we explore the methods for depolymerization of cellulose with a focus on catalytic partial hydrolysis to COS. Aspects of cellulose depolymerization using enzymes, homogeneous catalysts and heterogeneous catalysts are described. Methods for qualitative and quantitative characterization of COS are discussed along with future challenges in COS synthesis. Role of mechanocatalysis and other technologies in branched oligosaccharide synthesis is also explored for solvent free cellulose depolymerization.
机译:纤维素低聚糖(COS)是通过部分水解从纤维素中提取的小碳水化合物分子。当外部给药或食用COS时,COS对植物、动物和人类产生生理影响。它们作为人类和动物的益生元以及植物的激发子的潜力引起了人们对其合成和纯化的兴趣。目前,即使在研究所需的规模上,它们也缺乏可用性,这限制了该领域的进展。在这篇综述中,我们探讨了纤维素解聚的方法,重点是催化部分水解成COS。介绍了利用酶、均相催化剂和非均相催化剂进行纤维素解聚的方面。讨论了COS的定性和定量表征方法,以及COS合成的未来挑战。机械催化和其他技术在支链低聚糖合成中的作用也被探索用于无溶剂纤维素解聚。

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