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Resistive-Pulse Analysis of Nanoparticles

机译:纳米粒子的电阻脉冲分析

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The development of nanopore fabrication methods during the past decade has led to the resurgence of resistive-pulse analysis of nanoparticles. The newly developed resistive-pulse methods enable researchers to simultaneously study properties of a single nanoparticle and statistics of a large ensemble of nanoparticles. This review covers the basic theory and recent advances in applying resistive-pulse analysis and extends to more complex transport motion (e.g., stochastic thermal motion of a single nanoparticle) and unusual electrical responses (e.g., resistive-pulse response sensitive to surface charge), followed by a brief summary of numerical simulations performed in this field. We emphasize the forces within a nanopore governing translocation of low-aspect-ratio, nondeformable particles but conclude by also considering soft materials such as liposomes and microgels.
机译:在过去的十年中,纳米孔制造方法的发展导致了纳米颗粒电阻脉冲分析的复兴。新开发的电阻脉冲方法使研究人员能够同时研究单个纳米粒子的特性和大量纳米粒子的统计数据。这篇综述涵盖了应用电阻脉冲分析的基本理论和最新进展,并扩展到更复杂的传输运动(例如单个纳米粒子的随机热运动)和异常的电响应(例如对表面电荷敏感的电阻脉冲响应),接下来是对该领域中进行的数值模拟的简要概述。我们强调了纳米孔内控制低长宽比,不可变形颗粒移位的力,但最后还考虑了诸如脂质体和微凝胶之类的软质材料。

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