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Point-of-Care Platforms

机译:护理点平台

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摘要

Point-of-care applications are gaining increasing interest in clinical diagnostics and emergency applications. Biosensors are used to monitor the biomolecular interaction process between a disease biomarker and a recognition element such as a reagent. Essential are the quality and selectivity of the recognition elements and assay types used to improve sensitivity and to avoid nonspecific interactions. In addition, quality measures are influenced by the detection principle and the evaluation strategies. For these reasons, this review provides a survey and validation of recognition elements, assays, and various types of detection methods for point-of-care testing (POCT) platforms. Common applications of clinical parameters are discussed and considered. In this ever-changing field, a snapshot of current applications is needed. We provide such a snapshot by way of a table including literature citations and also discuss these applications in more detail throughout.
机译:即时医疗应用在临床诊断和急诊应用中越来越受到关注。生物传感器用于监测疾病生物标志物与识别元素(例如试剂)之间的生物分子相互作用过程。至关重要的是用于提高灵敏度和避免非特异性相互作用的识别元件和测定类型的质量和选择性。此外,质量措施还受检测原理和评估策略的影响。出于这些原因,此评论提供了针对即时检验(POCT)平台的识别元素,测定法和各种类型的检测方法的调查和验证。讨论并考虑了临床参数的常见应用。在这个不断变化的领域中,需要当前应用程序的快照。我们通过包括文献引文的表格的形式提供了这种快照,并且还将在全文中更详细地讨论这些应用程序。

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