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Endoscopic parathyroidectomy: a retrospective review of 27 cases

机译:内镜下甲状旁腺切除术:回顾性评论27例

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摘要

Background Primary hyperparathyroidism is a common endocrine disorder with adenomas being the most frequent cause. The condition is conventionally treated by a bilateral neck exploration through a cervical incision with removal of the affected glands. Intra-operative parathyroid hormone (IOPTH) monitoring and pre-operative Tc99m MIBI scans are facilitating focused approaches like minimally invasive video-assisted parathyroidectomy (MiVAP) and totally endoscopic parathyroidectomy (TOEP). Methods Patients with primary hyperparathyroidism were tested for location of diseased gland and accordingly selected for endoscopic parathyroidectomy by either trans-vestibular or trans-axillary approach. Those having undergone prior neck surgery or irradiation and those with an enlarged thyroid were excluded. All patients underwent IOPTH measurement to confirm the completeness of diseased gland resection. Results Eleven cases meeting selection criteria underwent endoscopic trans-vestibular parathyroidectomy and 16 cases underwent endoscopic trans-axillary parathyroidectomy. The mean operative time and blood loss were 104 min and 34 mL in trans-vestibular approach, respectively, while they were 47 min and 68 mL for the trans-axillary approach. All patients had post-operative resolution of hypercalcaemia. A single conversion to cervical approach was performed due to unsatisfactory IOPTH fall. A single patient suffered transient recurrent laryngeal nerve palsy which resolved with steroids. Conclusion Endoscopic parathyroidectomy is a safe and feasible surgical procedure when combined with pre-operative imaging and intra-operative parathyroid hormone monitoring. There is a steady rise in the number of patients with primary hyperparathyroidism, a majority of whom have solitary gland affliction. Focused exploration is the current standard, wherein endoscopic surgery can be an important tool to improve outcomes.
机译:背景原发性甲状旁腺功能亢进是一种常见的内分泌疾病,腺瘤是最常见的病因。这种情况通常通过宫颈切口进行双侧颈部探查并切除受影响的腺体来治疗。术中甲状旁腺激素(IOPTH)监测和术前Tc99m-MIBI扫描促进了微创视频辅助甲状旁腺切除术(MiVAP)和全内镜甲状旁腺切除术(TOEP)等聚焦方法。方法对原发性甲状旁腺功能亢进患者进行腺体定位检查,并据此选择经前庭或经腋窝的腔镜甲状旁腺切除术。之前接受过颈部手术或放疗的患者和甲状腺肿大的患者被排除在外。所有患者均接受眼压测量,以确认病变腺体切除的完整性。结果符合入选标准的11例患者行内镜下经前庭甲状旁腺切除术,16例患者行内镜下经腋窝甲状旁腺切除术。经前庭入路的平均手术时间和出血量分别为104min和34ml,而经腋窝入路的平均手术时间和出血量分别为47min和68ml。所有患者术后均出现高钙血症。由于眼压下降不理想,仅进行了一次转颈手术。一名患者出现一过性喉返神经麻痹,经类固醇治疗后症状缓解。结论内镜甲状旁腺切除术结合术前影像学检查和术中甲状旁腺激素监测是一种安全可行的手术方法。原发性甲状旁腺功能亢进症患者的数量稳步上升,其中大多数患者患有单发性腺体疾病。重点探查是当前的标准,内镜手术可以成为改善结果的重要工具。

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  • 来源
    《Surgical Endoscopy》 |2021年第3期|共8页
  • 作者单位

    Grant Med Coll Dept Gen Surg 6th Floor Main Hosp Bldg JJ Hosp Campus Mumbai 400008 Maharashtra;

    Grant Med Coll Dept Gen Surg 6th Floor Main Hosp Bldg JJ Hosp Campus Mumbai 400008 Maharashtra;

    Grant Med Coll Dept Gen Surg 6th Floor Main Hosp Bldg JJ Hosp Campus Mumbai 400008 Maharashtra;

    Govt Med Coll Dept Gen Surg Nagpur Maharashtra India;

    Grant Med Coll Dept Gen Surg 6th Floor Main Hosp Bldg JJ Hosp Campus Mumbai 400008 Maharashtra;

    Grant Med Coll Dept Gen Surg 6th Floor Main Hosp Bldg JJ Hosp Campus Mumbai 400008 Maharashtra;

    Grant Med Coll Dept Gen Surg 6th Floor Main Hosp Bldg JJ Hosp Campus Mumbai 400008 Maharashtra;

    Grant Med Coll Dept Gen Surg 6th Floor Main Hosp Bldg JJ Hosp Campus Mumbai 400008 Maharashtra;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 诊断学;
  • 关键词

    Endoscopic; Parathyroidectomy; Endocrine; Parathyroid; Hyperparathyroidism;

    机译:内镜;甲状旁腺切除术;内分泌;甲状旁腺;甲状旁腺机能亢进;

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