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首页> 外文期刊>Surgical Endoscopy >Trends of anti-reflux surgery in Denmark 2000-2017: a nationwide registry-based cohort study
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Trends of anti-reflux surgery in Denmark 2000-2017: a nationwide registry-based cohort study

机译：2000 - 2017年丹麦抗反动手术趋势：基于全国的注册管理机构的队列研究

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Background The utilisation of laparoscopic fundoplication peaked internationally around 2000. Perioperative morbidity, mortality, and length of stay initially declined as the use of laparoscopic technique increased. Studies indicate that complication rates have increased over time, probably as a consequence of rising age and level of comorbidity. None of these previous studies is nationwide. Therefore, this study aimed to investigate trends in the utilisation of anti-reflux surgery in the entire Danish population from 2000 to 2017. Methods Nationwide Danish health registries were utilised to include all Danish patients undergoing anti-reflux surgery 2000-2017. The utilisation of anti-reflux surgery in procedures per 100.000 inhabitants was compared to the utilisation of proton-pump inhibitors for each year. Postoperative complications, mortality, and length of stay per year, including yearly changes, were also calculated. Results The use of anti-reflux surgery peaked in 2001 with 5.9 procedures per 100,000 inhabitants and reached its lowest point in 2008 with 2.8 procedures per 100,000 inhabitants. The use of proton-pump inhibitors increased from 3,370 users per 100,000 inhabitants in 2000 to 10,284 users per 100,000 inhabitants in 2017. The 30-day and 90-day mortality ranged from 0 to 1.2%. The 30-day hospital-registered complications were 1.3-6.1%, and the 90-day hospital-registered complications were 2.4-8.3%. Length of stay was consistently low, with a median of 2 days in 2000 reduced to a median of 1 day by 2017. Conclusion The utilisation of anti-reflux surgery in Denmark from 2000 to 2017 declined, and the use of PPI increased dramatically. Age, comorbidity, and postoperative complications increased, while the use of laparoscopic technique remained high, and mortality was consistently low.
机译：背景2000年左右，腹腔镜胃底折叠术的使用在国际上达到顶峰。随着腹腔镜技术应用的增加，围手术期的发病率、死亡率和住院时间开始下降。研究表明，并发症的发生率随着时间的推移而增加，这可能是年龄和共病程度增加的结果。之前的这些研究都不是全国性的。因此，本研究旨在调查2000年至2017年期间整个丹麦人群中抗反流手术的使用趋势。方法利用丹麦全国卫生注册中心，纳入2000-2017年期间接受抗反流手术的所有丹麦患者。每10万居民中抗反流手术的使用率与每年质子泵抑制剂的使用率进行了比较。还计算了术后并发症、死亡率和每年的住院时间，包括每年的变化。结果抗反流手术的使用率在2001年达到峰值，每10万居民中有5.9例手术，2008年达到最低点，每10万居民中有2.8例手术。质子泵抑制剂的使用从2000年的每10万居民3370人增加到2017年的每10万居民10284人。30天和90天的死亡率在0到1.2%之间。30天住院记录的并发症为1.3-6.1%，90天住院记录的并发症为2.4-8.3%。住院时间一直较低，2000年的中位数为2天，2017年的中位数为1天。结论从2000年到2017年，丹麦抗反流手术的使用率下降，PPI的使用大幅增加。年龄、合并症和术后并发症增加，而腹腔镜技术的使用率仍然很高，死亡率一直很低。

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