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首页> 外文期刊>Annals of epidemiology >Dietary Patterns and the Risk of Breast Cancer.
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Dietary Patterns and the Risk of Breast Cancer.

机译：饮食习惯和患乳腺癌的风险。

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PURPOSE: Ecologic, migrant, and secular trend studies suggest an association between the Western diet and the risk of breast cancer. We examined data from the Nurses Health Study II to evaluate the association between major dietary patterns and the risk of breast cancer among pre-menopausal women. METHODS: We derived "Western" and "prudent" dietary patterns from the responses of 90,638 premenopausal women, aged 26 to 46 years at baseline in 1991, who completed validated food frequency questionnaires in 1991 and 1995. These patterns were then evaluated for their associations with risk of breast cancer. RESULTS: During 8 years of follow-up, we documented 710 cases of invasive breast cancer. The multivariate RR (95% CI) comparing highest to lowest quintiles of cumulative average score were 0.90 (0.68-1.18, p-value, test for trend = 0.54) for the prudent dietary pattern and 0.97 (0.71-1.33, p-value, test for trend = 0.97) for the Western dietary pattern. CONCLUSIONS: Our findings suggest that there is no overall association between dietary patterns and risk of breast cancer. However, we found an inverse association between the prudent dietary pattern and breast cancer risk among ever smokers, but the test for interaction was not significant. We suggest that this finding merits further evaluation.
机译：目的：生态，移民和长期趋势研究表明，西方饮食与乳腺癌风险之间存在关联。我们检查了来自“护士健康研究II”的数据，以评估绝经前女性的主要饮食习惯与乳腺癌风险之间的关联。方法：我们从1991年基线时年龄为26至46岁的90,638名绝经前妇女的反应中得出了“西方”和“审慎”的饮食模式，他们在1991年和1995年完成了经过验证的食物频率问卷调查，然后评估了这些模式的关联性有患乳腺癌的风险。结果：在8年的随访中，我们记录了710例浸润性乳腺癌。谨慎饮食模式的最高平均五分位数与最低五分位数的多元RR（95％CI）分别为0.90（0.68-1.18，p-值，趋势检验= 0.54）和0.97（0.71-1.33，p-value，西方饮食模式的趋势检验= 0.97）。结论：我们的研究结果表明饮食模式和患乳腺癌的风险之间没有整体关联。但是，我们发现谨慎的饮食习惯与吸烟者之间的乳腺癌风险呈反比关系，但相互作用的检验并不显着。我们建议这一发现值得进一步评估。

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