O-serotype distribution of Escherichia coli bloodstream infection isolates in critically ill patients in The Netherlands

Verboom D. M.; Varkila M. R. J.; Morrow B.; Davies T.; de Palacios P. Ibarra; Poolman J.; Hermans P. W. M.; Dudley E. G.; Roberts E.; Cremer O. L.; Bonten M. J. M.

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O-serotype distribution of Escherichia coli bloodstream infection isolates in critically ill patients in The Netherlands

机译：荷兰批评患者的大肠杆菌血流感染分离物的O-血清型分布

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Objectives: Invasive infections by extra-intestinal pathogenic Escherichia coli (ExPEC) strains are increasing. We determined O-serogroups of E. coli isolates from ICU patients having bloodstream infections (BSI) and the potential coverage of a 10-valent O-polysaccharide conjugate vaccine currently in development for the prevention of invasive ExPEC disease.

机译：目的：肠外致病性大肠杆菌（EXEC）菌株的侵袭性感染正在增加。我们测定了患有血液感染（BSI）的ICU患者的大肠杆菌分离株的O血清群，以及目前正在开发的预防侵袭性EXEC疾病的10价O-多糖结合疫苗的潜在覆盖率。

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《Vaccine》 |2021年第12期|共5页
作者
Verboom D. M.; Varkila M. R. J.; Morrow B.; Davies T.; de Palacios P. Ibarra; Poolman J.; Hermans P. W. M.; Dudley E. G.; Roberts E.; Cremer O. L.; Bonten M. J. M.;
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作者单位

Univ Med Ctr Utrecht Julius Ctr Hlth Sci &

Primary Care Utrecht Netherlands;

Univ Med Ctr Utrecht Julius Ctr Hlth Sci &

Primary Care Utrecht Netherlands;

Janssen Res &

Dev LLC Raritan NJ USA;

Janssen Res &

Dev LLC Raritan NJ USA;

Janssen Vaccines Bern Switzerland;

Janssen Vaccines &

Prevent BV Leiden Netherlands;

Univ Med Ctr Utrecht Julius Ctr Hlth Sci &

Primary Care Utrecht Netherlands;

Penn State Univ Dept Food Sci E Coli Reference Ctr University Pk PA 16802 USA;

Penn State Univ Dept Food Sci E Coli Reference Ctr University Pk PA 16802 USA;

Univ Med Ctr Utrecht Dept Intens Care Utrecht Netherlands;

Univ Med Ctr Utrecht Dept Med Microbiol Utrecht Netherlands;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Vaccine; Escherichia coli; ExPEC; ICU; Bloodstream infections;

机译：疫苗大肠杆菌;ExPEC;重症监护室;血流感染;

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O-serotype distribution of Escherichia coli bloodstream infection isolates in critically ill patients in The Netherlands

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