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Which first line antihypertensive?

机译:哪一条降压剂?

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摘要

Finally, a broadly applicable study to write about. LEGEND-HTN is a large scale, observational analysis using nine databases to identify the class of antihypertensive with the best cardiovascular outcomes when used singly. Thiazides and thiazide-like diuretics were the best, but you can be reassured ACE inhibitors, angiotensin receptor blockers, and calcium channel blockers weren't far behind. The advantages of this study are its size and its real world nature, as both these factors increase the generalisability of the findings. The disadvantages are that the data aren't randomised, and so are subject to confounding.
机译:最后,一项广泛适用的研究要写。 Legend-HTN是使用九个数据库进行大规模的观察性分析,以识别单独使用时最佳心血管结局的降压药类别。 噻嗪类和噻嗪类样利尿剂是最好的,但是您可以放心的ACE抑制剂,血管紧张素受体阻滞剂和钙通道阻滞剂不远。 这项研究的优势在于它的规模及其现实世界的本质,因为这两个因素都会增加发现的普遍性。 缺点是数据不是随机的,因此可能会混淆。

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