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首页> 外文期刊>BMJ: British medical journal >Fluoxetine for obsessive compulsive behaviours in autism
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Fluoxetine for obsessive compulsive behaviours in autism

机译:自闭症中强迫性行为的氟西汀

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摘要

Reddihough and colleagues performed a blinded randomised controlled trial of fluoxetine in children and adolescents with autism at three centres in Australia. The severity of the obsessive compulsive behaviours was reduced in the fluoxetine group compared with placebo, but this became null in the prespecified adjusted analysis. Treatment discontinuation rates were very high and no primary outcome data were available for 25% of participants, which make it difficult to know what value to place on the results.
机译:Reddihough及其同事在澳大利亚三个中心的自闭症儿童和青少年中对氟西汀进行了盲目的随机对照试验。 与安慰剂相比,氟西汀组的强迫性行为的严重程度降低了,但这在预先指定的调整后分析中无效。 治疗停用率很高,没有25%的参与者可用的主要结果数据,这使得很难知道在结果上要有什么价值。

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