FDA considers Alzheimer's drug abandoned after trial failures

Nigel Hawkes

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FDA considers Alzheimer's drug abandoned after trial failures

机译：FDA考虑了在审判失败后被放弃的阿尔茨海默氏症药物

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A drug for Alzheimer's disease that was abandoned after it failed in two phase III trials has been resurrected after a results analysis showed that, with the right dosage, it might work in patients with early stage disease. Aducanumab, developed by Biogen, joined a long list of failed Alzheimer's drugs this March after two trials found it did not slow the disease. A similar drug from Eli Lilly also failed, leading drug market analysts to conclude that the search for a treatment based on attacking amyloid plaques, the disease's pathological signature, was doomed.

机译：阿尔茨海默氏病的一种药物在两期试验中失败后被放弃，结果后，结果分析表明，在正确的剂量下，它可能在早期疾病的患者中起作用。由Biogen开发的Aducanumab在两次试验发现该疾病并没有减慢疾病后，今年3月加入了一长串失败的阿尔茨海默氏症药物。 Eli Lilly的类似药物也失败了，领导药物市场分析师得出的结论是，基于攻击淀粉样蛋白斑块（该疾病的病理签名）的治疗注定要失败。

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《BMJ: British medical journal》 |2019年第8220期|175-175|共1页
作者
Nigel Hawkes;
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正文语种英语
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experimentation; Trials; Amyloid Plaquedrug marketingClinical Trials, Phase III as TopicUnited States Food and Drug AdministrationPharmaceutical PreparationsabandonEmbedded Lisp Interpreter;

机译：实验;试验;淀粉样蛋白斑块营销典型试验;第三阶段作为主题非国家食品和药物管理药品制剂制剂abdandical posentiessabandonembandonembanded lisp lisp;

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FDA considers Alzheimer's drug abandoned after trial failures

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