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首页> 外文期刊>BMJ: British medical journal >(Misinterpreting studies on the adverse effects of statins
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(Misinterpreting studies on the adverse effects of statins

机译:(误解了他汀类药物的不良影响的研究

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Our study "Discontinuation of statins in routine care settings" has been cited in recent discussions in The BMJ on statin intolerance. Some of these reports misinterpreted our study. Our study sought to investigate the "real world" experience of patients who developed symptoms that they, or their healthcare providers, thought might have been caused by statins. Using natural language processingto analyse more than 100 000 patient records, we found that statin re-challenge after a presumed statin related event led in more than 90% of cases to patients taking a statin long term. We concluded "that many of the statin-related events may have other causes, are tolerable, or may be statin specific." Our findings were later confirmed in another large study.5 Taken together, we stand by our report, including our note of the study's limitations.
机译:在BMJ关于他汀类药物不耐受的最新讨论中,我们的研究“在常规护理环境中停止他汀类药物”。 其中一些报告误解了我们的研究。 我们的研究试图调查患者或其医疗保健提供者认为可能是他汀类药物引起的症状的患者的“现实世界”经历。 使用自然语言处理来分析超过1万名患者记录,我们发现他汀类药物在假定他汀类药物相关的事件后重新挑战了90%以上的病例,长期服用了他汀类药物。 我们得出结论:“许多与他汀类药物有关的事件可能具有其他原因,是可以忍受的,也可能是他汀类药物的。” 我们的发现后来在另一项大型研究中得到了证实。5总的来说,我们支持我们的报告,包括我们对研究的局限性的注意。

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