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The role of chemical exposures in reducing the effectiveness of water–sanitation–hygiene interventions in Bangladesh, Kenya, and Zimbabwe

机译:化学曝光在降低孟加拉国,肯尼亚和津巴布韦水的有效性中的作用

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Abstract The sustainable success of water, sanitation, and hygiene (WASH) interventions to reduce waterborne disease and promote public health in low‐income regions is uncertain. Recent large randomized controlled trials in Bangladesh, Kenya, and Zimbabwe revealed that traditional household WASH interventions are unlikely to reduce diarrhea or improve linear growth (i.e., reduce stunting) in infants and children—two important indicators of the effectiveness of WASH interventions. A possible factor contributing to the null results is that traditional WASH interventions control microbial pathogens but do not remove chemical toxicants. Exposure to many organic and inorganic chemical toxicants is associated with diarrheal symptoms, as well as with preterm birth and stunting. Many chemical toxicants have deleterious effects on the immune system, impairing the body's response to infectious diseases, and reducing the effectiveness of vaccinations. Globalization has led to rapid and largely unregulated import, production, use, and disposal without adequate treatment of large quantities of hazardous chemicals throughout the developing world, with profound effects on the environment and human health. Literature evidence from the past 10 to 15 years on putative and demonstrated chemical exposures in Bangladesh, Kenya, and Zimbabwe and the regions within the countries where the large WASH trials took place supports potential contribution(s) from chemical toxicants in the failure of traditional WASH interventions to relieve diarrhea and stunting. Mitigating exposures to organic and inorganic chemical immunotoxins through drinking water and other routes is likely to be a necessary‐but‐insufficient criterion for the sustainable success of WASH interventions. This article is categorized under: Engineering Water > Water, Health, and Sanitation Engineering Water > Sustainable Engineering of Water
机译:摘要水,卫生和卫生(WASH)干预措施的可持续成功,以减少水传播疾病并促进低收入地区的公共卫生。最近在孟加拉国,肯尼亚和津巴布韦进行的大型随机对照试验表明,传统的家庭洗手干预措施不太可能减少腹泻或改善婴儿和儿童的线性生长(即减少发育迟缓),这两个重要指标是清洗干预效果的重要指标。导致无效结果的可能因素是传统的洗发干预措施控制微生物病原体,但不能去除化学毒性。接触许多有机和无机化学有毒物质与腹泻症状以及早产和发育迟缓有关。许多化学有毒物质对免疫系统产生有害影响,损害了人体对传染病的反应,并降低了疫苗接种的有效性。全球化导致了迅速且在很大程度上不受管制的进口,生产,使用和处置,而在整个发展中国家的大量有害化学物质的情况下,对环境和人类健康产生了深远的影响。过去10到15年的文献证据在孟加拉国,肯尼亚和津巴布韦证明了化学曝光,以及进行大型洗涤试验进行的国家 /地区内的地区,这支持了从传统WASH失败的化学有毒物质的潜在贡献(S)减轻腹泻和发育迟缓的干预措施。通过饮用水和其他路线缓解对有机和无机化学免疫毒素的暴露可能是洗发干预措施可持续成功的必要(必需)标准。本文分类为:工程水>水,健康和卫生工程水>水的可持续工程

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