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Determinants of racial/ethnic disparities in disordered sleep and obesity

机译：睡眠和肥胖症中种族/种族差异的决定因素

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Racial/ethnic minorities experience a disproportionate risk of both suboptimal sleep and obesity, and the relationship between sleep and obesity may differ by race/ethnicity for modifiable and non-modifiable reasons. Because many people of color have historically lived and continue to largely live in disadvantaged, obesogenic physical and social environments, these greater adverse exposures likely negatively affect sleep, resulting in physiological dysregulation. Physiological dysregulation may, in turn, lead to increased obesity risk and subsequent health consequences, which are likely more influential than potential genetic differences in race, a social construct The purpose of this article is to describe potential environmental, genetic, and epigenetic determinants of racial/ethnic differences in the sleep-obesity relationship and to review current epidemiological findings regarding either racial/ethnic minority specific estimates of the association or disparities in the relationship. Using the socioecological framework as a conceptual model, I describe sleep and obesity as socially patterned and embedded in modifiable physical and social contexts with common causes that are influenced by upstream social conditions. I also provide examples of sleep and obesity-related studies that correspond with the downstream, intermediate, and upstream factors that likely contribute to commonly observed racial/ethnic disparities in the sleep-obesity relationship. The review concludes with broad recommendations for (1) advancing research methodology for epidemiological studies of disparities in the link between sleep and obesity, (2) future research topics, as well as (3) several broad policies and structures needed to address racial/ethnic disparities in sleep health and obesity.
机译：种族/族裔少数民族的睡眠和肥胖症的风险不成比例，睡眠与肥胖之间的关系可能因种族/民族而异，出于可修改和不可修改的原因。由于许多有色人种历史上已经生活并继续生活在不利的，肥胖的身体和社会环境中，因此这些更大的不良暴露可能会对睡眠产生负面影响，从而导致生理失调。生理失调又可能导致肥胖风险增加和随后的健康后果，这可能比种族中潜在的遗传差异更具影响力，本文的目的是描述潜在的环境，遗传和表观遗传学的决定因素/族裔肥胖关系中的差异，并回顾有关关系中的种族/族裔少数民族特定估计的当前流行病学发现或关系中的差异。我将社会生态框架作为一种概念模型，将睡眠和肥胖描述为具有社会和社会环境中的社会图案和嵌入，并具有受到上游社会条件影响的常见原因。我还提供了与睡眠，中间和上游因素相对应的睡眠和肥胖相关研究的例子，这些因素可能导致睡眠肥胖关系中通常观察到的种族/族裔差异。综述以（1）为流行病学研究的研究方法进行了广泛的建议，用于睡眠与肥胖之间的联系，（2）未来的研究主题，以及（3）解决种族/种族所需的几项广泛的政策和结构睡眠健康和肥胖的差异。

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