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Changing Interpretations and Cognitive Behavioral Therapy for Generalized Anxiety Disorder: A Randomized Trial

机译:变化的解释和普遍焦虑症的认知行为疗法:一项随机试验

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Among people with generalized anxiety disorder (GAD), those who have a stronger tendency to negatively interpret ambiguous situations benefit less from cognitive-behavioral therapy (CBT). Accordingly, an interpretation modification program (IMP) could improve the effectiveness of CBT for that anxious population. This randomized clinical trial evaluates the impact of adding an IMP to CBT for a GAD group. Our hypotheses are as follows: (1) the interpretation bias is correlated to the severity of pre-treatment GAD symptoms; (2) adding an IMP to CBT will contribute to great improvement of the interpretation bias; and (3) adding an IMP to CBT will lead to a greater reduction of GAD symptoms and depression. A randomized selection of participants (N=71) in 2 groups (CBT + IMP; CBT + Placebo training). The interpretation bias and severity of GAD symptoms are measured prior to treatment, in the middle of treatment and posttreatment. The results show that interpretation bias is positively correlated to the severity of pre-treatment GAD symptoms, r=.46, p=.001. Adding an IMP to CBT also leads to greater improvement of interpretation bias in ambiguous situations [F(2, 64.77)=4.22, p=.044, f(2)=.02]. Finally, the results observed do not support a greater reduction of GAD symptoms for the condition CBT=IMP [F(2, 126.16)=0.41, p=0.67, f(2)=.01]. Adding an IMP to CBT led to further reduction of participants' interpretation bias, but not of GAD symptoms.
机译:在患有普遍焦虑症(GAD)的患者中,那些倾向于对歧义情况进行负面解释的趋势更倾向于从认知行为疗法(CBT)中受益。因此,解释修改计划(IMP)可以提高CBT对焦虑人群的有效性。这项随机临床试验评估了为GAD组增加IMP的影响。我们的假设如下:(1)解释偏见与治疗前GAD症状的严重程度相关; (2)在CBT中添加IMP将有助于解释偏见的重大改善; (3)在CBT中添加IMP将导致GAD症状和抑郁症的减少。 2组的参与者随机选择(n = 71)(CBT + IMP; CBT +安慰剂训练)。在治疗和治疗中间,在治疗前测量了GAD症状的解释偏差和严重程度。结果表明,解释偏差与治疗前GAD症状的严重程度呈正相关,r = .46,p = .001。在CBT中添加一个IMP还会导致在模棱两可的情况下的解释偏差更大改善[F(2,64.77)= 4.22,p = .044,f(2)=。02]。最后,观察到的结果不支持较大的降低条件的GAD症状CBT = IMP [F(2,126.16)= 0.41,p = 0.67,F(2)=。01]。在CBT中添加一个IMP,导致参与者的解释偏见进一步减少,但没有增加GAD症状。

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