Correlation between white matter microstructure changes and cognitive function in type 2 diabetes assessed using diffusion tensor imaging

Yu Su; Jie Gao; Dongsheng ZhangMin TangFei QiMan WangXiaoling Zhang

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Correlation between white matter microstructure changes and cognitive function in type 2 diabetes assessed using diffusion tensor imaging

机译：使用扩散张量成像评估的2型糖尿病中的白质微结构变化与认知功能之间的相关性

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Type 2 diabetes mellitus (T2DM) is a risk factor for mild cognitive dysfunction and Alzheimer’s disease, but the related neural mechanisms are still unknown. Diffusion tensor imaging (DTI) can quantitatively evaluate the microstructure changes of the white matter of the brain. Although some studies have reported findings for white matter changes related to T2DM, the results were inconsistent. This review summarized 28 T2DM-related DTI studies from home and abroad. We found that the studies reported a wide range of white matter microstructure abnormalities in T2DM patients, and that changes in white matter structure in different regions in T2DM patients are related to specific cognitive functions. DTI is of great value in exploring the relationship between T2DM and white matter microstructure changes and cognitive dysfunction, which might provide imaging evidence in revealing the neural mechanisms underlying T2DM-related cognitive dysfunction.

机译：2型糖尿病（T2DM）是轻度认知功能障碍和阿尔茨海默氏病的危险因素，但相关的神经机制仍然未知。扩散张量成像（DTI）可以定量评估大脑白质的微观结构变化。尽管一些研究报告了与T2DM有关的白质变化的发现，但结果不一致。这篇评论总结了来自国内外的28个与T2DM相关的DTI研究。我们发现研究报告了T2DM患者的各种白质微结构异常，并且T2DM患者不同区域的白质结构的变化与特定的认知功能有关。 DTI在探索T2DM与白质微观结构变化和认知功能障碍之间的关系方面具有重要价值，这可能会提供成像证据，以揭示与T2DM相关认知功能障碍的神经机制。

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《Chinese journal of academic radiology.》 |2021年第1期|9-20|共12页
作者
Yu Su; Jie Gao; Dongsheng ZhangMin TangFei QiMan WangXiaoling Zhang;
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作者单位

Department of MRI, The Shaanxi Provincial People’s Hospital, No.256 Youyi West Road, Xi’an 710068;

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正文语种英语
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关键词
White Matter; cognitive function; CognitionType 2 Diabetes MellitusStructural changeCognitive DeclineDiffusion Tensor Imaging;

机译：白质;认知功能;认知型2糖尿病;

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机译：使用Diffusion Tensor Imaging指标区分高级别胶质瘤和转移性脑肿瘤

Correlation between white matter microstructure changes and cognitive function in type 2 diabetes assessed using diffusion tensor imaging

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