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>Therapeutic strategies for pyogenic liver abscess patients: a protocol proposed from the perspective of interventional radiologists
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Therapeutic strategies for pyogenic liver abscess patients: a protocol proposed from the perspective of interventional radiologists
This review aims to compare the different therapeutic strategies for pyogenic liver abscess (PLA) patients, and a protocol for PLA treatment was proposed, which was based on current evidence from the literature. Data cited in this review were obtained primarily from Pubmed up to November, 2020. Articles were selected with the search items “pyogenic liver abscess”, “hepatic abscess”, “bacterial hepatic abscess”, “percutaneous drainage”, “treatment” and “therapy”. After the summary in the current literature, image-guided percutaneous drainage (PD) combined with antibiotics is recommended as first-line therapy despite lacking consensus on the therapeutic strategies. Surgery is generally performed when PLA fails to respond to PD, or the patient has concomitant abdominal diseases. Antibiotics are usually used prior to PD or surgery and the regime could be adjusted according to the blood or/and abscess culture results. When the PLA patients presented with Acute Physiologic and Chronic Health Evaluation II score > 15 points, ICU admission should be considered to reduce the mortality risk. A protocol for PLA treatment was proposed. However, the accuracy of the proposed protocol should be validated in the further studies.
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