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DNA and information storage

机译:DNA和信息存储

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IT HAS never been part of professional KIM work to understand the intricacies of Deoxyribonucleic acid (or DNA). We should start getting interested in it now. It has been enough for us as lay people to know that DNA is the basis of genetics, and that it consists of molecules containing data and instructions that determine how all known organisms function. But bioinformaticians (notice the middle four syllables!) are beginning to get involved in that data bearing capacity - and if they and multidisciplinary teams of scientists can solve the practical problems, biological storage at a molecular level will be an option for massive amounts of information sourced from computer files. In the midst of the complexities, the best explanation I've come across is by Dr Nick Goldman of the European Biomedics Institute. In computer files information is stored as zeros and ones, and in DNA it's stored as As Cs Gs and Ts, (adenine, cytosine, guanine and thymine), and EMBL-EBI has invented a code which converts the former into the latter. In turn that means we have the possibility of storing the world's information in structures at the molecular level. Dr Emily Leproust of Twist Bioscience says: "If we stored all the data that is on the internet in DNA, that would be the size of a shoebox".
机译:理解脱氧核糖核酸(或DNA)的复杂性的专业KIM工作从来都不是专业工作的一部分。我们现在应该开始对此感兴趣。对于我们的外行人来说,已经足够知道DNA是遗传学的基础,并且由包含数据和指示的分子组成,这些分子决定了所有已知生物的运作方式。但是,生物信息学家(请注意中期四个音节!)开始参与该数据轴承能力 - 如果他们和科学家的多学科团队可以解决实际问题,那么在分子级别的生物存储将是大量信息的一种选择。来自计算机文件。在复杂性的过程中,我遇到的最好的解释是欧洲生物医学研究所的尼克·高盛(Nick Goldman)博士。在计算机文件中,信息存储为零和一个,在DNA中,它以CS GS和TS(腺嘌呤,胞嘧啶,鸟嘌呤和胸腺素)的形式存储,并且EMBL-EBI发明了将前者转换为后者的代码。反过来,这意味着我们有可能将世界信息存储在分子层的结构中。 Twist Bioscience的Emily Leproust博士说:“如果我们存储DNA中Internet上的所有数据,那将是鞋盒的大小”。

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