Survival Outcomes in Surgical Treatment of 72 Cases of Squamous Cell Carcinoma of the Temporal Bone

Fang Lu Chi; Feng Ming Gu; Chun Fu DaiBing ChenHua Wei Li

首页> 外文期刊>Otology and neurotology: official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology >Survival Outcomes in Surgical Treatment of 72 Cases of Squamous Cell Carcinoma of the Temporal Bone

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Survival Outcomes in Surgical Treatment of 72 Cases of Squamous Cell Carcinoma of the Temporal Bone

机译：72例颞骨鳞状细胞癌的手术治疗中的生存结果

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Objective: To evaluate surgical outcomes for squamous cell carcinoma of the temporal bone. Study Design: Retrospective study. Setting: Eye and ENT Hospital.Methods: Seventy-two patients with squamous cell carcinoma of the temporal bone were analyzed for survival. The patients were staged according to the modified Pittsburgh staging system. Five patients with Tl cancers underwent local resection (LR), and 10 patients with Tl cancers underwent lateral temporal bone resection (LTBR). Two patients with T2 cancers underwent LR, and 1 patient with T2 cancer underwent LTBR. One patient with T3 cancer underwent LR, 8 patients with T3 cancers underwent LTBR, and 10 patients with T3 cancers underwent subtotal temporal bone resection (STBR). Ten patients with T4 cancers underwent LTBR, and 25 patients with T4 cancers underwent STBR.Results: Of all patients that underwent surgery, 18 died of their disease during the follow-up time. The 5-year survival rates of patients with T stages 1 through 4 were 100%, 67%, 21%, and 14%, respectively. There was no statistically significant difference in 5-year survival rate between T3 and T4 using the log-rank test O > 0.05). The 5-year survival rates after LTBR and STBR for T3 were 26% and 16% (p > 0.05), respectively, and those for T4 were 17% and 11% (p > 0.05), respectively. Conclusion: An eh bloc resection is favored in an effort to produce negative surgical margins for squamous cell carcinoma of the.temporal bone. Adjunctive radiotherapy is used for advanced lesions.

机译：目的：评估颞骨鳞状细胞癌的手术结局。研究设计：回顾性研究。环境：ENT医院。方法：分析了颞骨鳞状细胞癌的72例生存。根据修改后的匹兹堡分期系统，将患者分期。 5例TL癌症患者接受了局部切除（LR），10例TL癌症患者接受了侧骨切除术（LTBR）。两名T2癌症患者接受了LR，1例T2癌患者接受了LTBR。一名T3癌症患者接受了LR，8例T3癌症患者接受了LTBR，10例T3癌症患者接受了颞骨切除次数（STBR）。十名T4癌症患者接受了LTBR，25例T4癌症患者接受了STBR。分析：在所有接受手术的患者中，有18例在随访期间死于其疾病。 T阶段1至4的患者的5年生存率分别为100％，67％，21％和14％。使用对数秩检验O> 0.05，T3和T4之间的5年生存率在5年生存率上没有统计学上的显着差异。 T3的LTBR和STBR后的5年生存率分别为26％和16％（P> 0.05），T4的生存率分别为17％和11％（P> 0.05）。结论：EH集团切除术是为了产生颞骨鳞状细胞癌的阴性手术缘。辅助放疗用于晚期病变。

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《Otology and neurotology: official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology》 |2011年第4期|665-669|共5页
作者
Fang Lu Chi; Feng Ming Gu; Chun Fu DaiBing ChenHua Wei Li;
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作者单位

Department of Otology and Skull Base Surgery, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China;

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原文格式 PDF
正文语种英语
中图分类耳鼻咽喉科学;
关键词
Squamous Cell Carcinoma; Temporal Bone; StagingT-3ThyroxineSurgerySurvival RateSurvivalOperative Surgical ProceduresPatientsNeoplasms;

机译：鳞状细胞癌;颞骨;stagingt-3甲状腺素外毛病毒率ravivalervival术手术程序patients neoplasmsms;

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4. A Survival Analysis of Patients with Localized, Asymptomatic Pancreatic Neuroendocrine Tumors: No Surgical Survival Benefit when Examining Appropriately Selected Outcomes [J] . Powers Benjamin D., Rothermel Luke D., Fleming Jason B., Journal of gastrointestinal surgery: official journal of the Society for Surgery of the Alimentary Tract . 2020,第12期

机译：A Survival Analysis of Patients with Localized, Asymptomatic Pancreatic Neuroendocrine Tumors: No Surgical Survival Benefit when Examining Appropriately Selected Outcomes
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机译：Adu; Aged;; Aged, 80 and over;; Cadherins;; Carcinoma, Squamous Cell;; Cell Nucleus;; Cytoplasm;; Female;; Humans;; Laryngeal Neoplasms;; Male;; Middle Aged;; Neoplasm Staging;; Protein-Serine-Threonine Kinases;; Proto-Oncogene Proteins c-akt;; Retrospective Studies;; beta Catenin;; *成年人;; 老年人;; 老年人, 80以上;; 钙粘着糖蛋白类;; 癌, 鳞状细胞;; 细胞核;; 细胞质;; 喉肿瘤;; 肿瘤分期;; 蛋白质丝氨酸苏氨酸激酶;; 回顾性研究
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机译：subamolide B Isolated from medicinal plantCinnamomum subavenium Induces Cytotoxicity in HumanCutaneous squamous Cell Carcinoma Cells throughmitochondrial and CHOp-Dependent Cell Death pathways

Survival Outcomes in Surgical Treatment of 72 Cases of Squamous Cell Carcinoma of the Temporal Bone

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