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首页> 外文期刊>Colorectal disease: the official journal of the Association of Coloproctology of Great Britain and Ireland >Level of vascular tie and its effect on functional outcome 2?years after anterior resection for rectal cancer
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Level of vascular tie and its effect on functional outcome 2?years after anterior resection for rectal cancer

机译：水平的血管系及其对功能的影响结果2 ?“癌症

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Abstract Aim Previous research indicates that high tie of the inferior mesenteric artery during anterior resection for rectal cancer might be associated with an increased risk of postoperative functional disturbances. The goal of this population‐based retrospective cohort study was to further investigate that association. Method Patients who underwent anterior resection for rectal cancer from April 2011 to September 2012 were identified through the Swedish Colorectal Cancer Registry. Bowel and urogenital function were assessed by a postal questionnaire 2?years after surgery. Information on the level of mesenteric tie and clinical variables was retrieved from the registry. The outcome was defined as any defaecatory, urinary or sexual dysfunction as reported by the patient. The association between high tie and the outcome was evaluated with multivariable logistic and linear regression with adjustment for confounders, such as sex, body mass index, comorbidity and preoperative radiation. Results With a response rate of 86%, 805 patients were included in the study. Of these, 46% were operated with high tie. After adjustment for confounders, high tie did not affect the risk of faecal incontinence ( OR 0.85; 95% CI 0.59–1.22), urinary incontinence ( OR 0.94; 95% CI 0.63–1.41) or various aspects of sexual dysfunction (erectile dysfunction, anejaculation, dyspareunia and coital vaginal dryness). However, an association between high tie and defaecation at night was detected ( OR 1.44; 95% CI 1.02–2.03). Conclusion This study does not support that the level of vascular tie influences the risk of major defaecatory, urinary or sexual disturbances 2?years after anterior resection for rectal cancer.
机译：抽象的目标之前的研究表明,高领带的肠系膜下动脉为直肠癌前切除术与风险增加有关术后功能障碍。基于人口重心的回顾性队列研究旨在进一步研究协会。从4月为直肠癌前切除术2011年至2012年9月被确定通过瑞典的结肠直肠癌注册表。由邮政泌尿生殖功能进行评估问卷2 ?在肠系膜领带和临床水平从注册表变量被检索。结果被定义为任何defaecatory,尿或性功能障碍患者报道。高领带和结果之间的关系评估和多变量逻辑吗线性回归与调整混杂因素,如性别、体重指数、疾病和术前辐射。反应率为86%,805名患者包括在这项研究。经营高领带。混杂因素,高领带没有影响的风险粪便尿失禁(或0.85;尿失禁(或0.94;或性功能障碍的各个方面(勃起功能障碍、anejaculation性交困难和性交阴道干涩)。高领带,澄清之间的联系晚上被发现(或1.44;结论本研究不支持的血管系影响的风险水平主要defaecatory尿或性干扰2呢?癌症。

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