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首页> 外文期刊>Vegetos: an international journal of plant research >Studies on phytochemical analysis, antioxidant and antibacterial activity of Ficus racemosa L. leaf and fruit extracts against wound pathogens
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Studies on phytochemical analysis, antioxidant and antibacterial activity of Ficus racemosa L. leaf and fruit extracts against wound pathogens

机译：植物化学的研究分析、抗氧化剂和抗菌活性的榕树racemosa l .叶子和水果提取物对伤口的病原体

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摘要

The present study deals with antibacterial activity of leaf and fruit parts of Ficus racemosa plant. Phytochemical analysis revealed alkaloids, flavonoids, phenols that contributed for higher antioxidant and antibacterial activity. The fruit exhibitedsignificant inhibition when compared with leaf. Bacteria from wounds of diabetic patients were isolated and identified as Staphylococcus spp., Pseudomonas spp., Klebsiella spp. and Escherichia coli. MIC for all the three (Ethanol, toluene and ethyl acetate) extracts was performed against wound isolates. Among all wound bacteria tested Staphylococcus spp. showed lowest MIC (0.07 mg/ml) with toluene extract of fruit. The MIC for E. coli and Pseudomonas spp. was found to be 0.15 mg/ ml and for Klebsiellaspp. (0.31 mg/ml).The MIC 0.625 mg/ml was obtained for toluene extracts of leaf against Staphylococcus spp. and Klebsiella spp. Antibacterial study revealed that the extracts of leaf and fruit exhibited good inhibition activity against wound isolates. Study of well diffusion assay of Ficus racemosa extract revealed that 75 and 100 mug/ml concentration was found to have significant control over wound pathogens. Highest inhibition was obtained for Staphylococcus spp. and Klebsiella spp. with fruit extractwith a zone of inhibition of 26 ± 0.10 and 24 ± 0.13 mm, respectively at 100 mug/ml. Toluene extract of fruit had higher antioxidant activity with IC50 of 0.75 mug/ml followed by ethanol extract 1.42 mug/ml and correlated with antibacterial activity.Thus, this study proved that leaf and fruit extract have significant antibacterial activity and hence it can be used for a therapeutic purpose.
机译：本研究涉及抗菌榕树的叶子和果实的部分地区的活动racemosa植物。生物碱、黄酮、酚类的贡献更高的抗氧化和抗菌活动。抑制与叶片相比。糖尿病患者的伤口被孤立和确认为葡萄球菌spp,假单胞菌spp,克雷伯氏菌种虫害和大肠杆菌。所有这三个(乙醇、甲苯和乙醋酸)提取物对伤口进行隔离。葡萄球菌种虫害显示麦克风(0.07最低毫克/毫升)和甲苯提取的水果。大肠杆菌和假单胞菌0.15种虫害被发现毫克/毫升,Klebsiellaspp。麦克风0.625毫克/毫升获得甲苯萃取物叶对葡萄球菌种虫害克雷伯氏菌抗菌研究表明spp叶的提取物和水果好展出对伤口隔离抑制活动。榕树racemosa提取的扩散试验显示,75年和100年杯/毫升浓度发现有显著控制伤口病原体。葡萄球菌种虫害和克雷伯氏菌种虫害水果extractwith抑制区26±24±0.10和0.13毫米,分别为100杯/毫升。抗氧化活性的IC50 0.75杯/毫升乙醇提取1.42杯/毫升和紧随其后与抗菌活性有关。研究证明了的叶子和果实中提取显著的抗菌活性,因此它可用于治疗目的。

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