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首页> 外文期刊>EMBO Journal >Think globally, act locally: How bacteria integrate local decisions with their global cellular programme
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Think globally, act locally: How bacteria integrate local decisions with their global cellular programme

机译:放眼全球,立足本地:细菌与他们的全球整合当地的决定cellular方案

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摘要

It has long been speculated that the bacterial second messenger c-di-GMP, a key molecular switch of bacterial community behaviour and persistence, can trigger specific cellular processes both on a global level as well as through some local action that prevents crosstalk originating from rapid diffusion of the signalling molecule. In this issue, Lindenberg et al (2013) report on a mechanism that not only helps to explain how spatial sequestration of c-di-GMP signalling components could be organized within bacterial cells, but also demonstrates how global and local command levels are interconnected.
机译:长期以来人们一直推测细菌第二信使c-di-GMP,一个关键的分子开关的细菌社区行为和持久性,可以触发特定的细胞过程都在吗全球层面以及通过一些当地行动阻止相声来自快速信号分子的扩散。问题,Lindenberg et al(2013)报告机制,不仅有助于解释空间封存c-di-GMP信号组件可以组织内细菌细胞,但也展示了全球和地方命令水平是相互联系的。

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