• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Disease Prevention Daily. >New Colon Cancer Study Findings Have Been Reported by Researchers at Department of General Surgery (Lack of Association Between Mir-146a Rs2910164 C/g Locus and Colorectal Cancer: From a Case-control Study To a Meta-analysis)
【24h】

New Colon Cancer Study Findings Have Been Reported by Researchers at Department of General Surgery (Lack of Association Between Mir-146a Rs2910164 C/g Locus and Colorectal Cancer: From a Case-control Study To a Meta-analysis)

机译：新结肠癌研究结果的报告普通外科学系的研究人员(mir - 146 a Rs2910164之间缺乏联系C / g轨迹和结肠直肠癌:从一个病例对照研究分析)

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

2021 MAY 03 (NewsRx)-By a News Reporter-Staff News Editor at Disease Prevention Daily-Investigators publish new report on Oncology - Colon Cancer. According to news reporting from Jiangsu, People's Republic of China, by NewsRx journalists, research stated, "Previous studies suggested that miR-146a rs2910164 (C/G) locus was predicted to influence the risk of cancer. However, the relationship of miR-146a rs2910164 locus with colorectal cancer (CRC) susceptibility was controversial." Financial support for this research came from Application and Basic Research Project of Changzhou City. The news correspondents obtained a quote from the research from the Department of General Surgery, "We recruited 1003 CRC patients and 1303 controls, and performed a case-control study to clarify the correlation of miR-146a rs2910164 locus with CRC risk. Subsequently, a comprehensive meta-analysis was conducted to verify our findings. In the case-control study, we suggested that miR-146a rs2910164 variants did not alter CRC risk (CG vs. CC: adjusted P=0.465; GG vs. CC: adjusted P=0.436, CG/GG vs. CC: adjusted P=0.387 and GG vs. CC/CG: adjusted P=0.589), even in subgroup analysis. Next, we conducted a pooled-analysis to identify the correlation of miR-146a rs2910164 locus with CRC risk. In this pooled-analysis, 7947 CRC cases and 12,168 controls were included. We found that miR-146a rs2910164 polymorphism did not influence the risk of CRC (G vs. C: P=0.537; GG vs. CC: P=0.517, CG/GG vs. CC: P=0.520 and GG vs. CC/CG: P=0.167). Our findings suggest that miR-146a rs2910164 C/G polymorphism is not correlated with the susceptibility of CRC."
机译：2021年5月03 (NewsRx)——一个新闻记者的新闻在疾病预防Daily-Investigators编辑器发布的新报告在肿瘤学,结肠癌。根据江苏、新闻报道中华人民共和国NewsRx记者,研究指出:“先前的研究建议mir - 146 a rs2910164 (C / G)轨迹预测影响患癌症的风险。然而,mir - 146 a rs2910164之间的关系与结直肠癌(CRC)易感性位点是有争议的。”研究来自应用和基础研究常州城市的项目。记者引用研究获得的我们的普通外科。招募了1003名CRC病人和1303个对照组,并进行了病例对照研究来澄清mir - 146 a的相关性与CRC rs2910164轨迹风险。是我们研究结果进行了验证。病例对照研究中,我们建议mir - 146 ars2910164变异没有改变CRC风险(CG vs。答:调整P = 0.465;P = 0.436, CG / GG和CC:调整P = 0.387和GG与CC / CG:调整P = 0.589),即使是在子群分析。识别mir - 146 a rs2910164的相关性轨迹与CRC的风险。7947 CRC病例和12168控制包括在内。我们发现mir - 146 a rs2910164多态性不影响风险的CRC (G和C: P = 0.537;GG和CC: P = 0.517, CG / GG和CC: P = 0.520和GG与CC / CG: P = 0.167)。mir - 146 a rs2910164 C / G多态性不是与CRC的易感性有关。”

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号