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Reports from Kaiser Permanente Washington Health Research Institute Add New Data to Findings in Dementia (Hemostatic Factor Levels and Cognitive Decline In Older Adults: the Cardiovascular Health Study)

机译:在华盛顿Kaiser Permanente健康报道研究所添加新的数据来发现痴呆(止血因素和认知水平下降的老年人:心血管健康研究)

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2021 MAY 03 (NewsRx) - By a News Reporter-Staff News Editor at Disease Prevention Daily - A new study on Neurodegenerative Diseases and Conditions - Dementia is now available. According to news originating from Seattle, Washington, by NewsRx correspondents, research stated, "Hemostasis is a key factor in cerebrovascular disease, but the association of hemostatic factors with cognitive decline is unclear. To prospectively evaluate associations of 20 hemostatic factor levels with changes in cognition during >= 8 years of follow-up in the Cardiovascular Health Study (CHS) of older adults." Funders for this research include NIH National Heart Lung & Blood Institute (NHLBI), NIH National Institute on Aging (NIA), NIH National Institute of Neurological Disorders & Stroke (NINDS). Our news journalists obtained a quote from the research from Kaiser Permanente Washington Health Research Institute, "We included participants of an existing CHS cross-sectional substudy (n = 400) with hemostatic factors measured in 1989-1990. Between 1989-1990 and 1998-1999, cognitive function was measured using the Modified Mini-Mental State Examination (3MSE) and Digit Symbol Substitution Tests. Mixed-effects linear regression models estimated change in cognitive function over time, adjusting for sociodemographic and clinical factors and APOE genotype, using Bonferroni adjustment.
机译:2021年5月03 (NewsRx)——由一个新闻记者新闻编辑在日常——一种新的疾病预防研究神经退行性疾病条件——痴呆现在可用。新闻来自西雅图,华盛顿NewsRx记者、研究说,“止血是脑血管的关键因素疾病,但止血的协会因素与认知功能减退尚不清楚。前瞻性评估协会20止血因素水平的变化认知在> = 8年的随访心血管健康研究(CHS)的老成年人。”国家心肺和血液研究所(NHLBI),国家卫生研究院的国家老龄研究所(NIA),国家卫生研究院国家神经疾病研究所&中风(研究所)。引用来自Kaiser Permanente的研究华盛顿健康研究所,“我们包括现有CHS的参与者横断面substudy (n = 400)止血因素以1989 - 1990。1989 - 1990和1998 - 1999年,认知功能用修改后的心理状况检查(3 mse)和数字符号替换测试。估计认知功能的变化随着时间的推移,调整社会人口和临床使用Bonferroni因子和载脂蛋白e基因型调整。

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