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首页> 外文期刊>Wound repair and regeneration: official publication of the Wound Healing Society [and] the European Tissue Repair Society >The impact of incisional negative pressure wound therapy on scar quality and patient-reported outcomes: A within-patient-controlled, randomised trial
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The impact of incisional negative pressure wound therapy on scar quality and patient-reported outcomes: A within-patient-controlled, randomised trial

机译:切口负压伤口的影响治疗疤痕的质量和patient-reported结果:within-patient-controlled,随机试验

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摘要

Literature provides a moderate level of evidence for the beneficial effects of incisional negative pressure wound therapy (iNPWT) on scar quality. The purpose of this study was to establish if iNPWT results in improved scar outcomes in comparison to the standard of care. Therefore, a within-patient randomised controlled, open-label trial was conducted in transgender men undergoing gender-affirming mastectomies. A unilateral side was randomised to receive iNPWT (PICO?, Smith&Nephew) without suction drains and contrastingly the standard dressing (Steri-Strips?) with suction drain. Scar quality and questionnaires were bilaterally measured by means of objective assessments and patient-reported outcome measures (PROM) at 1, 3 and 12 months. Objective scar outcomes were scar pliability (Cutometer?), colouration (DSM-II) and scar width (3-D imaging). PROM outcomes were related to scars (POSAS and SCAR-Q) and body satisfaction (BODY-Q). From 85 included patients, 80 were included for analyses. No significant difference between treatments was seen in the quantitative outcomes of scar pliability, colour, and width. For qualitative scar outcomes, several significant findings for iNPWT were found for several subscales of the POSAS, SCAR-Q, and BODY-Q. These effects could not be substantiated with linear mixed-model regression, signifying no statically more favourable outcome for either treatment option. In conclusion, this study demonstrated that some PROM outcomes were more favourable for the iNPWT compared to standard treatment. In contrast, the quantitative outcomes showed no beneficial effects of iNPWT on scar outcomes. This suggests that iNPWT is of little benefit as a scarimproving therapy.
机译:文学提供了一个中等水平的证据的有利影响切口负面的压力伤口疗法(iNPWT)疤痕质量。本研究的目的是建立iNPWT导致疤痕结果的改善比较的标准护理。within-patient随机对照开放试验是在变性人接受gender-affirming乳房切除。是随机获得iNPWT (PICO ?没有吸排水和Smith&Nephew)与之相反的标准着装与吸入排水(Steri-Strips ?)。双边和问卷测量客观的评估和手段patient-reported结果措施(舞会)1、3和12个月。柔软(Cutometer ?),颜色(DSM-II)和疤痕宽度(3 d成像)。与疤痕(posa和SCAR-Q)和身体满意度(BODY-Q)。80包括了分析。不同治疗方法的定量的结果伤疤柔软,色彩,和宽度。重大发现为iNPWT被发现的几个分量表posa SCAR-Q,BODY-Q。线性混合模型回归,标志着没有静态的更有利的结果治疗的选择。证明一些舞会的结果是更多有利于iNPWT比标准治疗。显示没有iNPWT疤痕的有利影响结果。scarimproving治疗中获益。

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