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首页> 外文期刊>Hepatology research: the official journal of the Japan Society of Hepatology >Meta‐analysis of laparoscopic versus open liver resection for hepatocellular carcinoma
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Meta‐analysis of laparoscopic versus open liver resection for hepatocellular carcinoma

机译：Meta分析腹腔镜与开放的肝脏切除的肝细胞癌

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Aim The aim of this study was to evaluate the surgical safety and effectiveness of laparoscopic hepatectomy (LH) in short‐ and long‐term outcomes compared to open hepatectomy (OH) in patients treated for hepatocellular carcinoma (HCC). Methods An electronic search of reports published before August 2017 was carried out to identify comparative studies evaluating LH versus OH for HCC. Results A total of 5889 patients (2421 underwent LH; 3468 underwent OH) were included in our meta‐analysis from 47 studies. Laparoscopic hepatectomies were associated with favorable outcomes in terms of operative blood loss (mean difference [MD], ?147.27; 95% confidence interval [CI], ?217.00, ?77.55), blood transfusion requirement (odds ratio [OR], 0.51; 95% CI, 0.40, 0.65), pathologic resection margins (MD, 0.07; 95% CI, 0.02, 0.12; P ?=?0.01), R0 resection rate (OR, 1.34; 95% CI, 0.98, 1.84; P ?=?0.07), and length of hospital stay (MD, ?5.13; 95% confidence interval, ?6.23, ?4.03). There were no differences between the groups in overall survival (OS) at 1?year (OR, 1.41; 95% CI, 1.00, 1.98), 3?years (OR, 1.12; 95% CI, 0.93, 1.36), or 5?years (OR, 1.18; 95% CI, 0.94, 1.46), in disease‐free survival (DFS) at 1 (OR, 1.19; 95% CI, 0.94, 1.51), 3?years (OR, 1.07; 95% CI, 0.86, 1.33), or 5?years (OR, 1.13; 95% CI, 0.92, 1.40), or in recurrence (OR, 0.90; 95% CI, 0.74, 1.08). Conclusion Compared to OH, LH is superior in terms of lower intraoperative blood loss and the requirement for blood transfusion, larger pathologic resection margins, increased R0 resection rates, and shorter length of hospital stay. Laparoscopic hepatectomy and OH have similar OS, DFS, and recurrence.
机译：目的本研究的目的是评估腹腔镜的手术的安全性和有效性肝切除术(LH)在短期和长期的结果相比开放肝切除术(OH)的病人治疗肝细胞癌(HCC)。方法电子搜索的报告发表2017年8月之前进行了识别比较研究评估LH与哦肝细胞癌。经历了LH;从47元量分析研究。肝切除术是有利的结果手术失血(平均而言差异(MD), 147.27;(CI), 217.00 ? 77.55),输血需求(优势比[或],0.51;0.65),病理切除边缘(医学博士,0.07;95%可信区间,0.02,0.12;(优势比,1.34;住院时间(医学博士? 5.13;置信区间,6.23 ? 4.03)。整个团体之间的区别生存在1 (OS)吗?1.98), 3 ?5？疾病检测自由生存(DFS) 1 (OR, 1.19;CI, 0.94, 1.51), 3 ?1.33),还是5 ?或复发(or, 0.90;结论相比,哦,LH优越降低术中失血和要求输血、大病理切除利润率,R0增加医院切除率和较短的长度留下来。类似的操作系统,DFS和复发。

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